Infant botulism, type F, presenting at 54 hours of life

Corinne A. Keet, Christine K. Fox, Marta Margeta, Elysa Marco, Andi L. Shane, Stephen J. DeArmond, Jonathan B. Strober, Steven P. Miller

Research output: Contribution to journalArticlepeer-review

Abstract

We report a case of botulism in a 54-hour-old infant with rapidly progressive fulminant paralysis and rapid spontaneous recovery atypical for infant botulism. Clostridium baratii and type F botulinum neurotoxin were isolated from the patient's stool. This unique presentation with rapid recovery is consistent with pharmacokinetics of type F botulinum neurotoxin. Interestingly, a muscle biopsy also revealed pathologic changes early in the disease course. This article reports the youngest known case of infant botulism and only the third reported case of this disease caused by type F neurotoxin. Botulism should be considered in patients of any age with subacute or acute neuromuscular weakness.

Original languageEnglish (US)
Pages (from-to)193-196
Number of pages4
JournalPediatric Neurology
Volume32
Issue number3
DOIs
StatePublished - Mar 2005
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

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