@article{8e12bf2c94924bedb968e1881f8759e1,
title = "Induction of pancreatic dna damage and nodules in rats treated with n-nitrosobis(2-oxopropyl)amine and n-nitroso(2-hydroxypropyl)(2-oxopropyl)amine",
abstract = "DNA damage was demonstrated by alkaline elution analysis in pancreas of rats treated with 100 mg/kg N-nitrosobis(2-oxopropyl)amine (BOP) and 20 mg/kg N-nitroso(2-hydroxy-propyl)2-oxopropyl)amine (HPOP). Young rats were treated with a single dose of BOP or HPOP and autopsied 4 months later. Histologically the pancreases contained multiple foci and nodules of atypical acinar cells which were not seen in controls.",
author = "Longnecker, {Daniel S.} and Joanne Zurlo and Curphey, {Thomas J.} and Adams, {William E.}",
note = "Funding Information: We acknowledge the technical assistance of Charles I.Coon, Elna T.Kuhl-mann, Joan Johnson, and Richard Marldey. This work was supported by grants CA 19410 from the National Cancer Institute through the National Pancreatic Cancer Project, CA 17843 from the NCI and NCI postdoctoral fellowship F32 CAO6855 to Joanne Zurlo.",
year = "1982",
doi = "10.1093/carcin/3.6.715",
language = "English (US)",
volume = "3",
pages = "715--717",
journal = "Carcinogenesis",
issn = "0143-3334",
publisher = "Oxford University Press",
number = "6",
}