TY - JOUR
T1 - Indoor charcoal smoke and acute respiratory infections in young children in the Dominican Republic
AU - Bautista, Leonelo E.
AU - Correa, Adolfo
AU - Baumgartner, Jill
AU - Breysse, Patrick
AU - Matanoski, Genevieve M.
PY - 2009/3
Y1 - 2009/3
N2 - The authors investigated the effect of charcoal smoke exposure on risks of acute upper and lower respiratory infection (AURI and ALRI) among children under age 18 months in Santo Domingo, Dominican Republic (1991-1992). Children living in households using charcoal for cooking (exposed, n = 201) were age-matched to children living in households using propane gas (nonexposed, n = 214) and were followed for 1 year or until 2 years of age. Fuel use and new episodes of AURI and ALRI were ascertained biweekly through interviews and medical examinations. Household indoor-air concentration of respirable particulate matter (RPM) was measured in a sample of follow-up visits. Incidences of AURI and ALRI were 4.4 and 1.4 episodes/child-year, respectively. After adjustment for other risk factors, exposed children had no significant increase in risk of AURI but were 1.56 times (95% confidence interval: 1.23, 1.97) more likely to develop ALRI. RPM concentrations were higher in charcoal-using households (27.9 μg/m 3 vs. 17.6 μg/m3), and ALRI risk increased with RPM exposure (10-μg/m3 increment: odds ratio = 1.17, 95% confidence interval: 1.02, 1.34). Exposure to charcoal smoke increases the risk of ALRI in young children, an effect that is probably mediated by RPM. Reducing charcoal smoke exposure may lower the burden of ALRI among children in this population.
AB - The authors investigated the effect of charcoal smoke exposure on risks of acute upper and lower respiratory infection (AURI and ALRI) among children under age 18 months in Santo Domingo, Dominican Republic (1991-1992). Children living in households using charcoal for cooking (exposed, n = 201) were age-matched to children living in households using propane gas (nonexposed, n = 214) and were followed for 1 year or until 2 years of age. Fuel use and new episodes of AURI and ALRI were ascertained biweekly through interviews and medical examinations. Household indoor-air concentration of respirable particulate matter (RPM) was measured in a sample of follow-up visits. Incidences of AURI and ALRI were 4.4 and 1.4 episodes/child-year, respectively. After adjustment for other risk factors, exposed children had no significant increase in risk of AURI but were 1.56 times (95% confidence interval: 1.23, 1.97) more likely to develop ALRI. RPM concentrations were higher in charcoal-using households (27.9 μg/m 3 vs. 17.6 μg/m3), and ALRI risk increased with RPM exposure (10-μg/m3 increment: odds ratio = 1.17, 95% confidence interval: 1.02, 1.34). Exposure to charcoal smoke increases the risk of ALRI in young children, an effect that is probably mediated by RPM. Reducing charcoal smoke exposure may lower the burden of ALRI among children in this population.
KW - Air pollution, indoor
KW - Biomass
KW - Charcoal
KW - Dominican Republic
KW - Particulate matter
KW - Respiratory tract infections
KW - Smoke
KW - Wood
UR - http://www.scopus.com/inward/record.url?scp=60149089508&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=60149089508&partnerID=8YFLogxK
U2 - 10.1093/aje/kwn372
DO - 10.1093/aje/kwn372
M3 - Article
C2 - 19126589
AN - SCOPUS:60149089508
SN - 0002-9262
VL - 169
SP - 572
EP - 580
JO - American journal of epidemiology
JF - American journal of epidemiology
IS - 5
ER -