Individualized Assessments in Treatment Research: An Examination of Parent-Nominated Target Problems in the Treatment of Disruptive Behaviors in Youth with Tourette Syndrome

Joseph F. McGuire, Denis G. Sukhodolsky, Karen Bearss, Heidi Grantz, Maryellen Pachler, Paul J. Lombroso, Lawrence Scahill

Research output: Contribution to journalArticlepeer-review

Abstract

Youth with Tourette syndrome (TS) often exhibit disruptive behaviors. Although improvement data on rating scales support the efficacy of structured psychotherapeutic interventions, there is growing interest in personalized outcome assessments. This report examined parent-nominated target problems (PTPs) as an individualized outcome measure in 48 youth with TS and disruptive behaviors, who participated in one of two randomized psychotherapy trials. At baseline, parents described two primary problems to an independent evaluator who generated a structured narrative for each problem. These narratives were reviewed and updated at endpoint. When rated by five treatment-blind judges, the PTP rating demonstrated excellent reliability and good convergent validity with the Disruptive Behavior Rating Scale (DBRS). The PTP rating exhibited comparable treatment effects to the DBRS, and accounted for additional variance in global treatment outcome. The PTP rating serves a reliable, valid, and sensitive personalized assessment in research trials that provides complementary information to standardized rating scales.

Original languageEnglish (US)
Pages (from-to)686-694
Number of pages9
JournalChild Psychiatry and Human Development
Volume45
Issue number6
DOIs
StatePublished - Dec 2014
Externally publishedYes

Keywords

  • Chronic tic disorders
  • Disruptive behaviors
  • Individualized assessment
  • Personalized mental healthcare
  • Treatment outcome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental and Educational Psychology
  • Psychiatry and Mental health

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