Incremental prognostic value of left ventricular global longitudinal strain in patients with aortic stenosis and preserved ejection fraction

Kenya Kusunose, Andrew Goodman, Roosha Parikh, Tyler Barr, Shikhar Agarwal, Zoran B. Popovic, Richard A. Grimm, Brian P. Griffin, Milind Y. Desai

Research output: Contribution to journalArticlepeer-review

Abstract

Background: We sought to assess the utility of left ventricular global longitudinal strain (LV-GLS) in predicting mortality in moderate to severe and paradoxical severe aortic stenosis (AS) patients with preserved ejection fraction. Methods and Results: We studied 395 AS patients (70±14 years, 57% men) with aortic valve area 2 evaluated between January to June 2008 (excluding severe other valve disease and LV ejection fraction 2), (b) standard severe (n=161; aortic valve area, ≤1 cm2; mean gradient ≥40 mm Hg), and (c) paradoxical severe (n=141; aortic valve area, ≤1 cm2 and mean gradient 2 increased from 48 to 58; P

Original languageEnglish (US)
Pages (from-to)938-945
Number of pages8
JournalCirculation: Cardiovascular Imaging
Volume7
Issue number6
DOIs
StatePublished - Nov 1 2014
Externally publishedYes

Keywords

  • Aortic stenosis
  • Outcomes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

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