Increasing positive outlook partially mediates the effect of empirically supported treatments on depression symptoms among adolescents

Rachel H. Jacobs, Sara J. Becker, John F. Curry, Susan G. Silva, Golda S. Ginsburg, David B. Henry, Mark A. Reinecke

Research output: Contribution to journalArticle

Abstract

Among adolescents there is evidence that cognitive change partially mediates the effect of cognitive behavioral therapy (CBT) on depression outcome. However, prior studies have been limited by small samples, narrow measures of cognition, and failure to compare cognitive change following CBT to cognitive change following antidepressant medication. This study examined whether change in four cognitive constructs (cognitive distortions, cognitive avoidance, positive outlook, and solution-focused thinking) mediated change in depression severity in a sample of 291 adolescents who participated in the Treatment for Adolescents with Depression Study (TADS). TADS assessed the effects of CBT, fluoxetine, and their combination on depression severity. All three treatments were associated with change in the cognitive constructs and combination treatment produced the greatest change. Furthermore, change in the cognitive constructs partially mediated change in depression severity within all three treatments. Results implicated positive outlook as the construct most associated with change in depression severity over 36 weeks.

Original languageEnglish (US)
Pages (from-to)3-19
Number of pages17
JournalJournal of Cognitive Psychotherapy
Volume28
Issue number1
DOIs
StatePublished - 2014

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Depression
Cognitive Therapy
Therapeutics
Fluoxetine
Cognition
Antidepressive Agents

Keywords

  • Adolescence
  • Cognition
  • Cognitive behavioral therapy
  • Depression
  • Mediation

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Experimental and Cognitive Psychology
  • Clinical Psychology

Cite this

Increasing positive outlook partially mediates the effect of empirically supported treatments on depression symptoms among adolescents. / Jacobs, Rachel H.; Becker, Sara J.; Curry, John F.; Silva, Susan G.; Ginsburg, Golda S.; Henry, David B.; Reinecke, Mark A.

In: Journal of Cognitive Psychotherapy, Vol. 28, No. 1, 2014, p. 3-19.

Research output: Contribution to journalArticle

Jacobs, Rachel H. ; Becker, Sara J. ; Curry, John F. ; Silva, Susan G. ; Ginsburg, Golda S. ; Henry, David B. ; Reinecke, Mark A. / Increasing positive outlook partially mediates the effect of empirically supported treatments on depression symptoms among adolescents. In: Journal of Cognitive Psychotherapy. 2014 ; Vol. 28, No. 1. pp. 3-19.
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