Increased very long chain fatty acids in patients on a ketogenic diet: A cause of diagnostic confusion

Christiane Theda; Robert C. Woody; Sakkubai Naidu; Ann B. Moser; Hugo W. Moser

doi:10.1016/S0022-3476(06)80013-2

Increased very long chain fatty acids in patients on a ketogenic diet: A cause of diagnostic confusion

Christiane Theda, Robert C. Woody, Sakkubai Naidu, Ann B. Moser, Hugo W. Moser

Kennedy Krieger Institute

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

We found an elevation of very long chain fatty acids in 13 of 22 plasma samples from patients on a ketogenic diet for the treatment of uncontrolled seizures. Because elevated values of very long chain fatty acids are a biochemical manifestation of peroxisomal dysfunction, this phenomenon might lead to diagnostic confusion. Thus the history and clinical status should be considered when plasma levels of very long chain fatty acids are interpreted.

Original language	English (US)
Pages (from-to)	724-726
Number of pages	3
Journal	The Journal of pediatrics
Volume	122
Issue number	5
DOIs	https://doi.org/10.1016/S0022-3476(06)80013-2
State	Published - May 1993

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/S0022-3476(06)80013-2

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abstract = "We found an elevation of very long chain fatty acids in 13 of 22 plasma samples from patients on a ketogenic diet for the treatment of uncontrolled seizures. Because elevated values of very long chain fatty acids are a biochemical manifestation of peroxisomal dysfunction, this phenomenon might lead to diagnostic confusion. Thus the history and clinical status should be considered when plasma levels of very long chain fatty acids are interpreted.",

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AU - Moser, Ann B.

AU - Moser, Hugo W.

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AB - We found an elevation of very long chain fatty acids in 13 of 22 plasma samples from patients on a ketogenic diet for the treatment of uncontrolled seizures. Because elevated values of very long chain fatty acids are a biochemical manifestation of peroxisomal dysfunction, this phenomenon might lead to diagnostic confusion. Thus the history and clinical status should be considered when plasma levels of very long chain fatty acids are interpreted.

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Increased very long chain fatty acids in patients on a ketogenic diet: A cause of diagnostic confusion

Abstract

ASJC Scopus subject areas

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