Increased oxygen consumption in human visual cortex: Response to visual stimulation

M. S. Vafaee, S. Marrett, E. Meyer, A. C. Evans, A. Gjedde

Research output: Contribution to journalArticle

Abstract

To test whether a sufficiently complex visual stimulus causes the consumption of oxygen to rise in the human visual cortex, we used positron emission tomography (PET) to measure the cerebral metabolic rate of oxygen (CMRO2) during visual stimulation in 6 healthy normal volunteers. A yellow- blue checkerboard, reversing its contrast at a frequency of 8 Hz, was presented for a period of 7 min, beginning 4 min before the onset of a 3-min scan. In the baseline condition, subjects fixated a cross-hair from 30 s before until the end of the 3-min scan. The CMRO2 was calculated with the two-compartment weighted integration method (1). The checkerboard minus baseline subtraction yielded statistically significant increases in CMRO2 in the primary (V1) and higher order visual cortices (V4 and V5). The significant CMRO2 increases were detected in these regions in both the group average and in each individual subject.

Original languageEnglish (US)
Pages (from-to)85-89
Number of pages5
JournalActa Neurologica Scandinavica
Volume98
Issue number2
StatePublished - 1998
Externally publishedYes

Fingerprint

Photic Stimulation
Visual Cortex
Oxygen Consumption
Healthy Volunteers
Positron-Emission Tomography
Hair
Oxygen

Keywords

  • CMRO
  • PET
  • Visual cortex

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Vafaee, M. S., Marrett, S., Meyer, E., Evans, A. C., & Gjedde, A. (1998). Increased oxygen consumption in human visual cortex: Response to visual stimulation. Acta Neurologica Scandinavica, 98(2), 85-89.

Increased oxygen consumption in human visual cortex : Response to visual stimulation. / Vafaee, M. S.; Marrett, S.; Meyer, E.; Evans, A. C.; Gjedde, A.

In: Acta Neurologica Scandinavica, Vol. 98, No. 2, 1998, p. 85-89.

Research output: Contribution to journalArticle

Vafaee, MS, Marrett, S, Meyer, E, Evans, AC & Gjedde, A 1998, 'Increased oxygen consumption in human visual cortex: Response to visual stimulation', Acta Neurologica Scandinavica, vol. 98, no. 2, pp. 85-89.
Vafaee, M. S. ; Marrett, S. ; Meyer, E. ; Evans, A. C. ; Gjedde, A. / Increased oxygen consumption in human visual cortex : Response to visual stimulation. In: Acta Neurologica Scandinavica. 1998 ; Vol. 98, No. 2. pp. 85-89.
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