Increased HLA—B Heterozygosity with Age

P. J. Converse, D. R.R. Williams

Research output: Contribution to journalArticlepeer-review

Abstract

427 healthy individuals ranging in age from 16 to 101 years were tested for HLA—A and—B antigens. No significant differences were found for any particular antigen according to the age of the individual. However, a significant trend of increasing frequency with age was found for individuals possessing two detectable HLA—B antigens. An apparent trend of increasing frequencies for individuals possessing four HLA—A and—B antigens was not significant. These results concur with those of some previously published studies.

Original languageEnglish (US)
Pages (from-to)275-278
Number of pages4
JournalTissue Antigens
Volume12
Issue number4
DOIs
StatePublished - Oct 1978

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Biochemistry
  • Genetics

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