Increased HLA-B heterozygosity with age

P. J. Converse, D. R R Williams


427 healthy individuals ranging in age from 16 to 101 years were tested for HLA-A and -B antigens. No significant differences were found for any particular antigen according to the age of the individual. However, a significant trend of increasing frequency with age was found for individuals possessing two detectable HLA-B antigens. An apparent trend of increasing frequencies for individuals possessing four HLA-A and -B antigens was not significant. These results concur with those of some previously published studies.

Original languageEnglish (US)
Pages (from-to)275-278
Number of pages4
JournalTissue Antigens
Issue number4
Publication statusPublished - 1978
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology
  • Immunology

Cite this

Converse, P. J., & Williams, D. R. R. (1978). Increased HLA-B heterozygosity with age. Tissue Antigens, 12(4), 275-278.