Increased 30-day mortality associated with carbapenem-resistant Enterobacteriaceae in children

Kathleen Chiotos, Pranita D. Tamma, Kelly B. Flett, Manjiree V. Karandikar, Koorosh Nemati, Warren B. Bilker, Theoklis Zaoutis, Jennifer H. Han

Research output: Contribution to journalArticlepeer-review

Abstract

In this multicenter study, we identified an increased risk of 30-day mortality among hospitalized children with carbapenem-resistant Enterobacteriaceae (CRE) isolated from clinical cultures compared with those with carbapenem-susceptible Enterobacteriaceae. We additionally report significant variation in antibiotic treatment for children with CRE infections with infrequent use of combination therapy.

Original languageEnglish (US)
JournalOpen Forum Infectious Diseases
Volume5
Issue number10
DOIs
StatePublished - Oct 1 2018

Keywords

  • Gram-negative resistance
  • Klebsiella pneumoniae carbapenemase
  • Multidrug-resistant organism
  • Pediatrics

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology

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