Inconsistent designs of association studies: A missed opportunity

T. G. Schulze, J. Hardy, F. J. McMahon

Research output: Contribution to journalArticlepeer-review

Abstract

Genetic association mapping is a powerful tool to detect susceptibility genes for complex disorders, even when each of these genes has small contribution to risk. Given the lack of Consistency across studies, particularly of psychiatric diseases, it is imperative to develop and agree upon standards for the design and report of genetic association studies. The authors propose standards of general study design, diagnostic assessment, genotyping, and statistical analysis, which could enhance the comparability of future genetic association studies.

Original languageEnglish (US)
Pages (from-to)770-772+767
JournalMolecular psychiatry
Volume8
Issue number9
DOIs
StatePublished - 2003
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience

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