Incidence of Local Recurrence and Port Site Metastasis After Laparoscopic Radical Nephroureterectomy

Michael Muntener, Edward M. Schaeffer, Frederico R. Romero, Matthew E. Nielsen, Mohamad E Allaf, Fabio Augusto R Brito, Christian Pavlovich, Louis R. Kavoussi, Thomas W. Jarrett

Research output: Contribution to journalArticle

Abstract

Objectives: To address the incidence of local recurrence and port site metastasis in patients who underwent laparoscopic radical nephroureterectomy (RNU) for upper tract transitional cell carcinoma (TCC). Methods: Between August 1993 and February 2006 116 laparoscopic RNU were performed in 115 patients at our institution. A traditional open excision, a laparoscopic stapler resection or a different approach was used for the management of the distal ureter in 76, 27, and 11 cases, respectively. Clinical follow-up as well as perioperative and pathologic data were retrospectively collected. Results: Perioperative and pathologic data were available in all 116 cases. Clinical outcomes were available in 107 patients with a mean follow-up of 30.5 months (range 1 to 148). Six patients (5.6%) had a local recurrence develop, including 1 patient with port site metastasis (0.9%) at an average of 5.7 months. In 2 of these patients, violation of the ipsilateral urinary tract was noted perioperatively. Conclusions: We report, in this large single-center series of laparoscopic RNU, a low incidence of local recurrence. Our results confirm that a laparoscopic approach to upper tract TCC does not result in a clinically significant increased risk of tumor spillage provided that principles of oncologic surgery are followed.

Original languageEnglish (US)
Pages (from-to)864-868
Number of pages5
JournalUrology
Volume70
Issue number5
DOIs
StatePublished - Nov 2007

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Neoplasm Metastasis
Recurrence
Incidence
Transitional Cell Carcinoma
Ureter
Urinary Tract
Neoplasms

ASJC Scopus subject areas

  • Urology

Cite this

Muntener, M., Schaeffer, E. M., Romero, F. R., Nielsen, M. E., Allaf, M. E., Brito, F. A. R., ... Jarrett, T. W. (2007). Incidence of Local Recurrence and Port Site Metastasis After Laparoscopic Radical Nephroureterectomy. Urology, 70(5), 864-868. https://doi.org/10.1016/j.urology.2007.07.027

Incidence of Local Recurrence and Port Site Metastasis After Laparoscopic Radical Nephroureterectomy. / Muntener, Michael; Schaeffer, Edward M.; Romero, Frederico R.; Nielsen, Matthew E.; Allaf, Mohamad E; Brito, Fabio Augusto R; Pavlovich, Christian; Kavoussi, Louis R.; Jarrett, Thomas W.

In: Urology, Vol. 70, No. 5, 11.2007, p. 864-868.

Research output: Contribution to journalArticle

Muntener, M, Schaeffer, EM, Romero, FR, Nielsen, ME, Allaf, ME, Brito, FAR, Pavlovich, C, Kavoussi, LR & Jarrett, TW 2007, 'Incidence of Local Recurrence and Port Site Metastasis After Laparoscopic Radical Nephroureterectomy', Urology, vol. 70, no. 5, pp. 864-868. https://doi.org/10.1016/j.urology.2007.07.027
Muntener, Michael ; Schaeffer, Edward M. ; Romero, Frederico R. ; Nielsen, Matthew E. ; Allaf, Mohamad E ; Brito, Fabio Augusto R ; Pavlovich, Christian ; Kavoussi, Louis R. ; Jarrett, Thomas W. / Incidence of Local Recurrence and Port Site Metastasis After Laparoscopic Radical Nephroureterectomy. In: Urology. 2007 ; Vol. 70, No. 5. pp. 864-868.
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AU - Nielsen, Matthew E.

AU - Allaf, Mohamad E

AU - Brito, Fabio Augusto R

AU - Pavlovich, Christian

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