Incidence of influenza virus infection in early infancy: A prospective study in South Asia

Emily Henkle, Mark C. Steinhoff, Saad B. Omer, Eliza Roy, Shams E. Arifeen, Rubhana Raqib, Monica McNeal, Robert F. Breiman, William J. Moss, K. Zaman

Research output: Contribution to journalArticle

Abstract

We evaluated infant sera from an immunization trial in Bangladesh to assess influenza hemagglutination inhibition antibody titer increases in 131 unimmunized infants from birth to 6 months. We detected 31 serologically defined infections. Combined with 10 additional rapid test-proven influenza cases, the minimal estimated incidence was 31 of 100 infants (95% CI: 24-41). These data suggest a high burden of influenza in young infants in tropical South Asia.

Original languageEnglish (US)
Pages (from-to)170-173
Number of pages4
JournalPediatric Infectious Disease Journal
Volume30
Issue number2
DOIs
StatePublished - Feb 2011

Keywords

  • infants
  • influenza

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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    Henkle, E., Steinhoff, M. C., Omer, S. B., Roy, E., Arifeen, S. E., Raqib, R., McNeal, M., Breiman, R. F., Moss, W. J., & Zaman, K. (2011). Incidence of influenza virus infection in early infancy: A prospective study in South Asia. Pediatric Infectious Disease Journal, 30(2), 170-173. https://doi.org/10.1097/INF.0b013e3181f63c39