Incidence and Prevalence of Dementia in Elderly Adults with Mental Retardation Without Down Syndrome

Warren B. Zigman, Nicole Schupf, Darlynne A. Devenny, Charles Miezejeski, Robert Ryan, Tiina K. Urv, Romaine Schubert, Wayne Silverman

Research output: Contribution to journalArticle

Abstract

Rates of dementia in adults with mental retardation without Down syndrome were equivalent to or lower than would be expected compared to general population rates, whereas prevalence rates of other chronic health concerns varied as a function of condition. Given that individual differences in vulnerability to Alzheimer's disease have been hypothesized to be due to variation in cognitive reserve, adults with mental retardation, who have long-standing intellectual and cognitive impairments, should be at increased risk. This suggests that factors determining intelligence may have little or no direct relationship to risk for dementia and that dementia risk for individuals with mental retardation will be comparable to that of adults without mental retardation unless predisposing risk factors for dementia are also present.

Original languageEnglish (US)
Pages (from-to)126-141+194
JournalAmerican Journal on Mental Retardation
Volume109
Issue number2
DOIs
StatePublished - Mar 2004

ASJC Scopus subject areas

  • Education
  • Rehabilitation
  • Developmental and Educational Psychology
  • Health Professions(all)

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    Zigman, W. B., Schupf, N., Devenny, D. A., Miezejeski, C., Ryan, R., Urv, T. K., Schubert, R., & Silverman, W. (2004). Incidence and Prevalence of Dementia in Elderly Adults with Mental Retardation Without Down Syndrome. American Journal on Mental Retardation, 109(2), 126-141+194. https://doi.org/10.1352/0895-8017(2004)109<126:IAPODI>2.0.CO;2