Inactivation of human immunodeficiency virus type 1 reverse transcriptase by oltipraz: Evidence for the formation of a stable adduct

Medicine & Life Sciences

• oltipraz 88%
• Human immunodeficiency virus 1 reverse transcriptase 71%
• HIV-1 45%
• DNA Polymerase I 11%
• Coloring Agents 9%
• Gel Chromatography 8%
• Chromatography 7%
• procion yellow 7%
• 1,2-dithiol-3-thione 7%
• diethanolamine 7%
• Enzymes 6%
• Mono Q 6%
• Anticarcinogenic Agents 5%
• Kinetics 5%
• Sulfhydryl Reagents 5%
• Ligands 5%
• HIV-2 5%
• Ion Exchange Chromatography 5%
• Anions 4%
• Cysteine 3%
• Inhibitory Concentration 50 3%
• Antiviral Agents 3%
• Temperature 2%
• Amino Acids 2%
• T-Lymphocytes 2%
• Cell Line 2%
• Proteins 1%

Chemical Compounds

• Oltipraz 100%
• Adduct 37%
• Label 7%
• Cys-Ser 6%
• Anticarcinogenic Agent 6%
• Sulfhydryl Reagent 5%
• Diethanolamine 5%
• Cysteine Residue 4%
• Ion-Exchange Chromatography 4%
• Size Exclusion Chromatography 3%
• Reaction Stoichiometry 3%
• Chromatography 3%
• Purification 2%
• Block Like Crystal 2%
• Dye 2%
• Ambient Reaction Temperature 2%
• pH Value 1%
• Protein 1%
• Acid 1%