In vivo tracking techniques for cellular regeneration, replacement, and redirection

Erik H.J.G. Aarntzen, Mangala Srinivas, Piotr Walczak, Miroslaw Janowski, Arend Heerschap, I. Jolanda M. De Vries, Carl G. Figdor, Jeff W.M. Bulte, Wim J.G. Oyen

Research output: Contribution to journalReview articlepeer-review

Abstract

Cellular therapy can be defined as the transplantation of living cells for the treatment of medical conditions. Three main objectives of cellular therapy are regeneration of damaged tissue, replacement of function by secretion of biologically active molecules, and redirection of aberrant processes. Given the complex nature of these approaches, in vivo tracking of the transplanted cells is critical to evaluate their potential benefit and to optimize treatment strategies. Recent advances are reviewed that enable in vivo cell tracking as an important adjunct to implement cellular therapy in clinical practice.

Original languageEnglish (US)
Pages (from-to)1825-1828
Number of pages4
JournalJournal of Nuclear Medicine
Volume53
Issue number12
DOIs
StatePublished - Dec 1 2012

Keywords

  • Cellular therapy
  • In vivo imaging
  • Regenerative medicine
  • Tracking
  • Transplantation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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