In vivo thermal evaluation of a subretinal prosthesis using an integrated resistance temperature detector

Ching Yu Liu, Frank Yang, Chia He Chung, Zung Hua Yang, Ta Ching Chen, Chang Hao Yang, Chung May Yang, Long Sheng Fan

Research output: Contribution to journalArticle

Abstract

The temperature rise from the operation of implanted biomedical devices should be kept within a safe limit to prevent thermal damage or any undesirable thermal effects. To evaluate the temperature rise from the operation of an implanted high-density microelectrodes array (MEA) on a flex in the subretinal space, we directly integrated resistance temperature detectors into this retinal MEA device in the same micro fabrication. We surgically implanted this MEA device in the subretinal space of a rabbit model and measured the temperature rise in vivo. The measured temperature rise is consistent with the calculated values from the finite element method. Experiment showed the temperature versus power dissipation of the MEA device had a slope of 0.84°C/(mW • mm -2). To ensure the temperature rise is within 1.0°C, the maximum power dissipation on the retinal implant should be kept within 1.2 mW • mm-2.

Original languageEnglish (US)
Article number13198
JournalJournal of Micro/Nanolithography, MEMS, and MOEMS
Volume13
Issue number1
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Detectors
Microelectrodes
evaluation
detectors
Temperature
temperature
Energy dissipation
dissipation
Microfabrication
rabbits
Prostheses and Implants
Hot Temperature
Thermal effects
temperature effects
finite element method
slopes
damage
Finite element method
fabrication
Experiments

Keywords

  • flexible electronics
  • resistance temperature detector
  • retinal prosthesis

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Atomic and Molecular Physics, and Optics

Cite this

In vivo thermal evaluation of a subretinal prosthesis using an integrated resistance temperature detector. / Liu, Ching Yu; Yang, Frank; Chung, Chia He; Yang, Zung Hua; Chen, Ta Ching; Yang, Chang Hao; Yang, Chung May; Fan, Long Sheng.

In: Journal of Micro/Nanolithography, MEMS, and MOEMS, Vol. 13, No. 1, 13198, 2014.

Research output: Contribution to journalArticle

Liu, Ching Yu ; Yang, Frank ; Chung, Chia He ; Yang, Zung Hua ; Chen, Ta Ching ; Yang, Chang Hao ; Yang, Chung May ; Fan, Long Sheng. / In vivo thermal evaluation of a subretinal prosthesis using an integrated resistance temperature detector. In: Journal of Micro/Nanolithography, MEMS, and MOEMS. 2014 ; Vol. 13, No. 1.
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