In vivo proton MR spectroscopy of the human brain

Research output: Contribution to journalReview articlepeer-review

Abstract

The advances in magnetic resonance spectroscopy (MRS) have enabled its in vivo application to obtain the images of brains. 1 MRS has the advantage over all other nuclei that it uses exactly the same hardware as used in conventional magnetic resonance imaging (MRI). Proton MRS of the brain gives useful information on the number of different neurological and psychiatric disorders. Such information is important in planning surgical excision or targeting localized radiotherapy. The technique plays an important role in evaluating adult, primary brain tumors. it is used in evaluating brain tumors in response to therapy. It is also heavily used as a research tool to better understand the pathophysiology of neurological disease in vivo and as a means of monitoring effects of treatment.

Original languageEnglish (US)
Pages (from-to)99-128
Number of pages30
JournalProgress in Nuclear Magnetic Resonance Spectroscopy
Volume49
Issue number2
DOIs
StatePublished - Sep 30 2006

Keywords

  • Brain
  • Magnetic resonance spectroscopy
  • Metabolism
  • Pulse sequences

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Nuclear and High Energy Physics
  • Spectroscopy

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