In vivo measurement of T2(*) and field inhomogeneity maps in the human heart at 1.5 T

Scott B. Reeder, Anthony Z. Faranesh, Jerrold L. Boxerman, Elliot R. McVeigh

Research output: Contribution to journalArticlepeer-review

154 Scopus citations


Cardiac echo-planar imaging suffers invariably from regions of severe distortion and T2(*) decay in the myocardium. The purpose of this work was to perform local measurements of T2(*) and field inhomogeneities in the myocardium and to identify the sources of focal signal loss and distortion. Field inhomogeneity maps and T2(*) were measured in five normal volunteers in short-axis slices spanning from base to apex. It was found that T2(*) ranged from 26 ms (SD = 7 ms, n = 5) to 41 ms (SD = 11 ms, n = 5) over most of the heart, and peak-to-peak field inhomogeneity differences were 71 Hz (SD = 14 Hz, n = 5). In all hearts, regions of severe signal loss were consistently adjacent to the posterior vein of the left ventricle; T2(*) in these regions was 12 ms (SD = 2 ms, n = 5), and the difference in resonance frequency with the surrounding myocardium was 70-100 Hz. These effects may be caused by increased magnetic susceptibility from deoxygenated blood in these veins.

Original languageEnglish (US)
Pages (from-to)988-998
Number of pages11
JournalMagnetic Resonance in Medicine
Issue number6
StatePublished - Jun 1998


  • Cardiac imaging
  • Echo planar imaging
  • Field inhomogeneities
  • Relaxation parameters

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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