In vivo imaging of MSCs

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Clinical applications of mesenchymal stromal/stem cells (MSCs) to treat a myriad of diseases are currently being initiated. For MSC therapy to become common practice, basic questions about the fate of MSCs once administered need to be addressed. These include the biodistribution, survival, and differentiation of MSCs. In this chapter, several imaging techniques are described that can be used to interrogate these questions in a clinically applicable manner, and several examples are discussed. Single-photon emission computed tomography (SPECT)/radioisotope imaging and magnetic resonance imaging (MRI) cell-tracking techniques are the two modalities that likely will become mainstays in clinical practice.

Original languageEnglish (US)
Title of host publicationMesenchymal Stromal Cells
Subtitle of host publicationBiology and Clinical Applications
PublisherSpringer New York
Pages389-402
Number of pages14
ISBN (Electronic)9781461457114
ISBN (Print)9781461457107
DOIs
StatePublished - Jan 1 2013

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'In vivo imaging of MSCs'. Together they form a unique fingerprint.

Cite this