In vivo demonstration of photoacoustic-guided liver surgery

Kelley M. Kempski, Alycen Wiacek, Jasmin Palmer, Michelle Graham, Eduardo González, Bria Goodson, Derek Allman, Huayu Hou, Sarah Beck, Jin He, Muyinatu A. Lediju Bell

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Liver surgeries carry considerable risk of injury to major blood vessels, which can lead to hemorrhaging and possibly patient death. Photoacoustic imaging is one solution to enable intraoperative visualization of blood vessels, which has the potential to reduce the risk of accidental injury to these blood vessels during surgery. This paper presents our initial results of a feasibility study, performed during laparotomy procedures on two pigs, to determine in vivo vessel visibility for photoacoustic-guided liver surgery. Delay-and-sum beamforming and coherence-based beamforming were used to display photoacoustic images and differentiate the signal inside blood vessels from surrounding liver tissue. Color Doppler was used to confirm vessel locations. Results lend insight into the feasibility of photoacoustic-guided liver surgery when the ultrasound probe is fixed and the light source is used to interrogate the surgical workspace.

Original languageEnglish (US)
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2019
EditorsAlexander A. Oraevsky, Lihong V. Wang
PublisherSPIE
ISBN (Electronic)9781510623989
DOIs
StatePublished - Jan 1 2019
EventPhotons Plus Ultrasound: Imaging and Sensing 2019 - San Francisco, United States
Duration: Feb 3 2019Feb 6 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10878
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2019
CountryUnited States
CitySan Francisco
Period2/3/192/6/19

Fingerprint

Photoacoustic effect
blood vessels
Blood vessels
liver
surgery
Liver
Surgery
Blood Vessels
Demonstrations
beamforming
Beamforming
vessels
swine
Wounds and Injuries
Feasibility Studies
visibility
death
Visibility
Laparotomy
Light sources

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Kempski, K. M., Wiacek, A., Palmer, J., Graham, M., González, E., Goodson, B., ... Lediju Bell, M. A. (2019). In vivo demonstration of photoacoustic-guided liver surgery. In A. A. Oraevsky, & L. V. Wang (Eds.), Photons Plus Ultrasound: Imaging and Sensing 2019 [108782T] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10878). SPIE. https://doi.org/10.1117/12.2510500

In vivo demonstration of photoacoustic-guided liver surgery. / Kempski, Kelley M.; Wiacek, Alycen; Palmer, Jasmin; Graham, Michelle; González, Eduardo; Goodson, Bria; Allman, Derek; Hou, Huayu; Beck, Sarah; He, Jin; Lediju Bell, Muyinatu A.

Photons Plus Ultrasound: Imaging and Sensing 2019. ed. / Alexander A. Oraevsky; Lihong V. Wang. SPIE, 2019. 108782T (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10878).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kempski, KM, Wiacek, A, Palmer, J, Graham, M, González, E, Goodson, B, Allman, D, Hou, H, Beck, S, He, J & Lediju Bell, MA 2019, In vivo demonstration of photoacoustic-guided liver surgery. in AA Oraevsky & LV Wang (eds), Photons Plus Ultrasound: Imaging and Sensing 2019., 108782T, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10878, SPIE, Photons Plus Ultrasound: Imaging and Sensing 2019, San Francisco, United States, 2/3/19. https://doi.org/10.1117/12.2510500
Kempski KM, Wiacek A, Palmer J, Graham M, González E, Goodson B et al. In vivo demonstration of photoacoustic-guided liver surgery. In Oraevsky AA, Wang LV, editors, Photons Plus Ultrasound: Imaging and Sensing 2019. SPIE. 2019. 108782T. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2510500
Kempski, Kelley M. ; Wiacek, Alycen ; Palmer, Jasmin ; Graham, Michelle ; González, Eduardo ; Goodson, Bria ; Allman, Derek ; Hou, Huayu ; Beck, Sarah ; He, Jin ; Lediju Bell, Muyinatu A. / In vivo demonstration of photoacoustic-guided liver surgery. Photons Plus Ultrasound: Imaging and Sensing 2019. editor / Alexander A. Oraevsky ; Lihong V. Wang. SPIE, 2019. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
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