TY - GEN
T1 - In vivo demonstration of photoacoustic-guided liver surgery
AU - Kempski, Kelley M.
AU - Wiacek, Alycen
AU - Palmer, Jasmin
AU - Graham, Michelle
AU - González, Eduardo
AU - Goodson, Bria
AU - Allman, Derek
AU - Hou, Huayu
AU - Beck, Sarah
AU - He, Jin
AU - Lediju Bell, Muyinatu A.
N1 - Funding Information:
This work was supported by NSF CAREER Award #1751522, REU Supplement to NSF CAREER Award #1751522, and the Computational Sensing & Medical Robotics Research Experience for Undergraduates program at Johns Hopkins University. The authors thank Nicholas Louloudis, Sue Eller, Ivan George, Dr. Lingdi Yin, and Dr. Liang Wang for animal care and surgery support and the Carnegie Center for Surgical Innovation. We also acknowledge the support of NVIDIA Corporation with the donation of the Titan Xp GPU that was used for portions of the signal processing required to display images presented in this paper.
Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.
PY - 2019
Y1 - 2019
N2 - Liver surgeries carry considerable risk of injury to major blood vessels, which can lead to hemorrhaging and possibly patient death. Photoacoustic imaging is one solution to enable intraoperative visualization of blood vessels, which has the potential to reduce the risk of accidental injury to these blood vessels during surgery. This paper presents our initial results of a feasibility study, performed during laparotomy procedures on two pigs, to determine in vivo vessel visibility for photoacoustic-guided liver surgery. Delay-and-sum beamforming and coherence-based beamforming were used to display photoacoustic images and differentiate the signal inside blood vessels from surrounding liver tissue. Color Doppler was used to confirm vessel locations. Results lend insight into the feasibility of photoacoustic-guided liver surgery when the ultrasound probe is fixed and the light source is used to interrogate the surgical workspace.
AB - Liver surgeries carry considerable risk of injury to major blood vessels, which can lead to hemorrhaging and possibly patient death. Photoacoustic imaging is one solution to enable intraoperative visualization of blood vessels, which has the potential to reduce the risk of accidental injury to these blood vessels during surgery. This paper presents our initial results of a feasibility study, performed during laparotomy procedures on two pigs, to determine in vivo vessel visibility for photoacoustic-guided liver surgery. Delay-and-sum beamforming and coherence-based beamforming were used to display photoacoustic images and differentiate the signal inside blood vessels from surrounding liver tissue. Color Doppler was used to confirm vessel locations. Results lend insight into the feasibility of photoacoustic-guided liver surgery when the ultrasound probe is fixed and the light source is used to interrogate the surgical workspace.
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U2 - 10.1117/12.2510500
DO - 10.1117/12.2510500
M3 - Conference contribution
AN - SCOPUS:85065432955
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Photons Plus Ultrasound
A2 - Oraevsky, Alexander A.
A2 - Wang, Lihong V.
PB - SPIE
T2 - Photons Plus Ultrasound: Imaging and Sensing 2019
Y2 - 3 February 2019 through 6 February 2019
ER -