In Vivo assessment of regional myocardial work in normal canine hearts using 3D tagged MRI

Haim Azhari; James L. Weiss; Edward P. Shapiro

doi:10.1007/978-1-4615-5959-7_20

In Vivo assessment of regional myocardial work in normal canine hearts using 3D tagged MRI

Haim Azhari, James L. Weiss, Edward P. Shapiro

School of Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A non-invasive method for assessing regional myocardial work is presented. The method utilizes tagged magnetic resonance images (MRI) obtained from two sets of orthogonal planes to mark and reconstruct 24 small myocardial cuboids at end-diastole (ED) and end-systole (ES) in the in vivo left ventricle (LV). Regional myocardial work is assessed by calculating the area enclosed by the endocardial wall tension-area (T-A) loop of each studied cuboid. The method was applied to six normal canine hearts. In addition, a global myocardial work index was obtained from the corresponding estimated pressure-volume (P-V) loops. The average work index calculated using the T-A loop was 0.242±0.088 J/100gr/beat, in agreement with the average index obtained from the P-V loop: 0.296± 0.089 J/100gr/beat. The two indices correlate linearly with a correlation coefficient of 0.82.

Original language	English (US)
Pages (from-to)	241-248
Number of pages	8
Journal	Advances in experimental medicine and biology
Volume	430
DOIs	https://doi.org/10.1007/978-1-4615-5959-7_20
State	Published - 1997

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1007/978-1-4615-5959-7_20

Cite this

@article{0eda45af6ab944aa80eaaed5be421aa8,

title = "In Vivo assessment of regional myocardial work in normal canine hearts using 3D tagged MRI",

abstract = "A non-invasive method for assessing regional myocardial work is presented. The method utilizes tagged magnetic resonance images (MRI) obtained from two sets of orthogonal planes to mark and reconstruct 24 small myocardial cuboids at end-diastole (ED) and end-systole (ES) in the in vivo left ventricle (LV). Regional myocardial work is assessed by calculating the area enclosed by the endocardial wall tension-area (T-A) loop of each studied cuboid. The method was applied to six normal canine hearts. In addition, a global myocardial work index was obtained from the corresponding estimated pressure-volume (P-V) loops. The average work index calculated using the T-A loop was 0.242±0.088 J/100gr/beat, in agreement with the average index obtained from the P-V loop: 0.296± 0.089 J/100gr/beat. The two indices correlate linearly with a correlation coefficient of 0.82.",

author = "Haim Azhari and Weiss, {James L.} and Shapiro, {Edward P.}",

year = "1997",

doi = "10.1007/978-1-4615-5959-7_20",

language = "English (US)",

volume = "430",

pages = "241--248",

journal = "Advances in experimental medicine and biology",

issn = "0065-2598",

publisher = "Springer New York",

}

TY - JOUR

T1 - In Vivo assessment of regional myocardial work in normal canine hearts using 3D tagged MRI

AU - Azhari, Haim

AU - Weiss, James L.

AU - Shapiro, Edward P.

PY - 1997

Y1 - 1997

N2 - A non-invasive method for assessing regional myocardial work is presented. The method utilizes tagged magnetic resonance images (MRI) obtained from two sets of orthogonal planes to mark and reconstruct 24 small myocardial cuboids at end-diastole (ED) and end-systole (ES) in the in vivo left ventricle (LV). Regional myocardial work is assessed by calculating the area enclosed by the endocardial wall tension-area (T-A) loop of each studied cuboid. The method was applied to six normal canine hearts. In addition, a global myocardial work index was obtained from the corresponding estimated pressure-volume (P-V) loops. The average work index calculated using the T-A loop was 0.242±0.088 J/100gr/beat, in agreement with the average index obtained from the P-V loop: 0.296± 0.089 J/100gr/beat. The two indices correlate linearly with a correlation coefficient of 0.82.

AB - A non-invasive method for assessing regional myocardial work is presented. The method utilizes tagged magnetic resonance images (MRI) obtained from two sets of orthogonal planes to mark and reconstruct 24 small myocardial cuboids at end-diastole (ED) and end-systole (ES) in the in vivo left ventricle (LV). Regional myocardial work is assessed by calculating the area enclosed by the endocardial wall tension-area (T-A) loop of each studied cuboid. The method was applied to six normal canine hearts. In addition, a global myocardial work index was obtained from the corresponding estimated pressure-volume (P-V) loops. The average work index calculated using the T-A loop was 0.242±0.088 J/100gr/beat, in agreement with the average index obtained from the P-V loop: 0.296± 0.089 J/100gr/beat. The two indices correlate linearly with a correlation coefficient of 0.82.

UR - http://www.scopus.com/inward/record.url?scp=0030799028&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030799028&partnerID=8YFLogxK

U2 - 10.1007/978-1-4615-5959-7_20

DO - 10.1007/978-1-4615-5959-7_20

M3 - Article

C2 - 9330733

AN - SCOPUS:0030799028

SN - 0065-2598

VL - 430

SP - 241

EP - 248

JO - Advances in experimental medicine and biology

JF - Advances in experimental medicine and biology

ER -

In Vivo assessment of regional myocardial work in normal canine hearts using 3D tagged MRI

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this