In vitro non-rigid life-size model of aortic arch aneurysm for endovascular prosthesis assessment

Abdulrazzaq Sulaiman, Loîc Boussel, Frédéric Taconnet, Jean Michel Serfaty, Hasan Alsaid, Cherif Attia, Laurent Huet, Philippe Douek

Research output: Contribution to journalArticle

Abstract

Purpose: It is essential to evaluate new stent designs before in vivo testing. The purpose of this study was to develop and validate a controlled and reproducible patient-derived process to produce a life-size in vitro model of aortic arch aneurysm for endovascular procedure simulation. Methods: A three-dimensional magnetic resonance angiography (3D MRA) image derived from a 60-year-old patient with aortic arch aneurysm was segmented using a home-made software package which allows one-click automatic segmentation of the aorta, meshing, and conversion to standard tessellation language (STL) format. A rapid prototyping technique established a stereolithographic model to produce a replica of the whole aorta, including the arch aneurysm and supra-aortic arteries. Results: The final model was made by pouring silicone rubber to obtain a sturdy, life-size, soft, transparent, plastic cast, accurately reproducing both the internal and external anatomy of the aortic aneurysm. This model was used under perfusion by an extracorporeal circulation pump, to test ex vivo stent deployment. Conclusion: The combination of easy segmentation and conversion to the STL format with industrial stereolithography techniques enabled a realistic silicon vascular phantom to be created for endovascular procedure simulation, image modality calibration, and new stent design.

Original languageEnglish (US)
Pages (from-to)53-57
Number of pages5
JournalEuropean Journal of Cardio-thoracic Surgery
Volume33
Issue number1
DOIs
StatePublished - Jan 2008
Externally publishedYes

Fingerprint

Aortic Aneurysm
Thoracic Aorta
Prostheses and Implants
Stents
Endovascular Procedures
Language
Surgical Casts
Silicone Elastomers
Extracorporeal Circulation
Magnetic Resonance Angiography
Silicon
Calibration
Blood Vessels
Aorta
Anatomy
Software
Arteries
Perfusion
In Vitro Techniques

Keywords

  • Aortic aneurysm
  • Interventional radiology
  • Stereolithography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

In vitro non-rigid life-size model of aortic arch aneurysm for endovascular prosthesis assessment. / Sulaiman, Abdulrazzaq; Boussel, Loîc; Taconnet, Frédéric; Serfaty, Jean Michel; Alsaid, Hasan; Attia, Cherif; Huet, Laurent; Douek, Philippe.

In: European Journal of Cardio-thoracic Surgery, Vol. 33, No. 1, 01.2008, p. 53-57.

Research output: Contribution to journalArticle

Sulaiman, A, Boussel, L, Taconnet, F, Serfaty, JM, Alsaid, H, Attia, C, Huet, L & Douek, P 2008, 'In vitro non-rigid life-size model of aortic arch aneurysm for endovascular prosthesis assessment', European Journal of Cardio-thoracic Surgery, vol. 33, no. 1, pp. 53-57. https://doi.org/10.1016/j.ejcts.2007.10.016
Sulaiman, Abdulrazzaq ; Boussel, Loîc ; Taconnet, Frédéric ; Serfaty, Jean Michel ; Alsaid, Hasan ; Attia, Cherif ; Huet, Laurent ; Douek, Philippe. / In vitro non-rigid life-size model of aortic arch aneurysm for endovascular prosthesis assessment. In: European Journal of Cardio-thoracic Surgery. 2008 ; Vol. 33, No. 1. pp. 53-57.
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