In vitro fertilization in women age 40 and older: The impact of assisted hatching

William B. Schoolcraft, Terry Schlenker, Georgeanna S. Jones, Howard W. Jones

Research output: Contribution to journalArticle

Abstract

Purpose: To assess the impact of assisted hatching on in vitro fertilization (IVF) outcome in women age 40 and older. Methods: A retrospective analysis was performed to compare 28 cycles of IVF without assisted hatching to 38 cycles of IVF with assisted hatching. All patients in both groups were age 40 or older and the mean age was similar. Results: The delivery rate per oocyte retrieval was significantly higher in the assisted hatching group (18/38; 48%) compared to the nonhatched controls (3/28; 11%, P=0.0003). The implantation rate of hatched embryos (40/175; 22%) was clearly enhanced, compared to the non-hatched embryos (7/126; 6%, P

Original languageEnglish (US)
Pages (from-to)581-584
Number of pages4
JournalJournal of Assisted Reproduction and Genetics
Volume12
Issue number9
DOIs
StatePublished - Oct 1995
Externally publishedYes

Fingerprint

Fertilization in Vitro
Embryonic Structures
Oocyte Retrieval
Age Groups

Keywords

  • age 40 and older
  • assisted hatching
  • implantation rate
  • in vitro fertilization
  • micromanipulation
  • zona pellucida

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology
  • Genetics
  • Developmental Biology

Cite this

In vitro fertilization in women age 40 and older : The impact of assisted hatching. / Schoolcraft, William B.; Schlenker, Terry; Jones, Georgeanna S.; Jones, Howard W.

In: Journal of Assisted Reproduction and Genetics, Vol. 12, No. 9, 10.1995, p. 581-584.

Research output: Contribution to journalArticle

Schoolcraft, William B. ; Schlenker, Terry ; Jones, Georgeanna S. ; Jones, Howard W. / In vitro fertilization in women age 40 and older : The impact of assisted hatching. In: Journal of Assisted Reproduction and Genetics. 1995 ; Vol. 12, No. 9. pp. 581-584.
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