In vitro activities of azithromycin, clarithromycin, erythromycin, and tetracycline against 13 strains of Chlamydia pneumoniae

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Abstract

Thirteen strains of Chlamydia pneumoniae were evaluated for their in vitro susceptibilities to azithromycin, clarithromycin, erythromycin, and tetracycline. The MIC ranges were 0.125 to 0.5 μg/ml for azithromycin, 0.031 to 1.0 μg/ml for clarithromycin, 0.125 to 1.0 μg/ml for erythromycin, and 0.125 to 1.0 μg/ml for tetracycline. The ranges for the minimal lethal concentrations were 0.125 to 0.5 μg/ml for azithromycin, 0.031 to 1.0 μg/ml for clarithromycin, 0.125 to 1.0 μg/ml for erythromycin, and 0.25 to 1.0 μg/ml for tetracycline. Clarithromycin and azithromycin were the most active antibiotics against C. pneumoniae in vitro.

Original languageEnglish (US)
Pages (from-to)212-214
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume40
Issue number1
DOIs
StatePublished - Jan 1996

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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