Abstract
Deoxyribonucleic acid techniques can be used to diagnose Duchenne muscular dystrophy prenatally in male fetuses that are at risk. Deoxyribonucleic acid-based prenatal diagnosis can be impossible when there is only one prior affected male and there is no identifiable deletion or alteration. We performed fetal muscle biopsy in utero in such a case and documented the presence of dystrophin, thereby confirming normality in a male fetus at risk. This first in utero experience adds fetal muscle biopsy to the available procedures for fetal tissue diagnosis.
Original language | English (US) |
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Pages (from-to) | 728-732 |
Number of pages | 5 |
Journal | American journal of obstetrics and gynecology |
Volume | 165 |
Issue number | 3 |
DOIs | |
State | Published - Sep 1991 |
Keywords
- Duchenne muscular dystrophy
- in utero muscle biopsy
- prenatal diagnosis
ASJC Scopus subject areas
- Obstetrics and Gynecology