In Structural Glycobiology, Deuterium provides the Details

Gerardo R. Vasta; L. Mario Amzel

doi:10.1016/j.str.2021.08.004

In Structural Glycobiology, Deuterium provides the Details

Gerardo R. Vasta, L. Mario Amzel

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

In this issue of Structure, Gadjos et al. (2021b) determine the structure of a bacterial lectin in complex with L-fucose by neutron diffraction of both perdeuterated protein and carbohydrate ligand. The structure provides insight into lectin-ligand interactions, opening avenues for drug design targeting bacterial lectins for intervention in infectious disease.

Original language	English (US)
Pages (from-to)	937-939
Number of pages	3
Journal	Structure
Volume	29
Issue number	9
DOIs	https://doi.org/10.1016/j.str.2021.08.004
State	Published - Sep 2 2021

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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10.1016/j.str.2021.08.004

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title = "In Structural Glycobiology, Deuterium provides the Details",

abstract = "In this issue of Structure, Gadjos et al. (2021b) determine the structure of a bacterial lectin in complex with L-fucose by neutron diffraction of both perdeuterated protein and carbohydrate ligand. The structure provides insight into lectin-ligand interactions, opening avenues for drug design targeting bacterial lectins for intervention in infectious disease.",

author = "Vasta, {Gerardo R.} and Amzel, {L. Mario}",

note = "Funding Information: Work was supported by grant IOS-1656720 from the National Science Foundation , R01GM070589 from the National Institutes of Health (to G.R.V.), and grant NIH HL050411 (to L.M.A.). Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",

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AU - Amzel, L. Mario

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N2 - In this issue of Structure, Gadjos et al. (2021b) determine the structure of a bacterial lectin in complex with L-fucose by neutron diffraction of both perdeuterated protein and carbohydrate ligand. The structure provides insight into lectin-ligand interactions, opening avenues for drug design targeting bacterial lectins for intervention in infectious disease.

AB - In this issue of Structure, Gadjos et al. (2021b) determine the structure of a bacterial lectin in complex with L-fucose by neutron diffraction of both perdeuterated protein and carbohydrate ligand. The structure provides insight into lectin-ligand interactions, opening avenues for drug design targeting bacterial lectins for intervention in infectious disease.

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In Structural Glycobiology, Deuterium provides the Details

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