In situ hybridization localizes the human putative oncogene GLI to chromosome subbands 12q13.3-14.1

Kristina Arheden; Mogens Rønne; Nils Mandahl; Sverre Heim; Kenneth W. Kinzler; Bert Vogelstein; Felix Mitelman

doi:10.1007/BF00288260

In situ hybridization localizes the human putative oncogene GLI to chromosome subbands 12q13.3-14.1

Kristina Arheden, Mogens Rønne, Nils Mandahl, Sverre Heim, Kenneth W. Kinzler, Bert Vogelstein, Felix Mitelman

School of Medicine

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Abstract

Using in situ hybridization, we have localized the human putative oncogene GLI to chromosome subbands 12q13.3-14.1. The precise genomic site is of interest since the region 12q13-15 has been found to be consistently rearranged in neoplasia-associated chromosome abnormalities in lipomas, myxoid liposarcomas, uterine leiomyomas, and pleomorphic adenomas of the salivary gland.

Original language	English (US)
Pages (from-to)	1-2
Number of pages	2
Journal	Human genetics
Volume	82
Issue number	1
DOIs	https://doi.org/10.1007/BF00288260
State	Published - Apr 1 1989

ASJC Scopus subject areas

Genetics
Genetics(clinical)

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abstract = "Using in situ hybridization, we have localized the human putative oncogene GLI to chromosome subbands 12q13.3-14.1. The precise genomic site is of interest since the region 12q13-15 has been found to be consistently rearranged in neoplasia-associated chromosome abnormalities in lipomas, myxoid liposarcomas, uterine leiomyomas, and pleomorphic adenomas of the salivary gland.",

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AU - Arheden, Kristina

AU - Rønne, Mogens

AU - Mandahl, Nils

AU - Heim, Sverre

AU - Kinzler, Kenneth W.

AU - Vogelstein, Bert

AU - Mitelman, Felix

PY - 1989/4/1

Y1 - 1989/4/1

N2 - Using in situ hybridization, we have localized the human putative oncogene GLI to chromosome subbands 12q13.3-14.1. The precise genomic site is of interest since the region 12q13-15 has been found to be consistently rearranged in neoplasia-associated chromosome abnormalities in lipomas, myxoid liposarcomas, uterine leiomyomas, and pleomorphic adenomas of the salivary gland.

AB - Using in situ hybridization, we have localized the human putative oncogene GLI to chromosome subbands 12q13.3-14.1. The precise genomic site is of interest since the region 12q13-15 has been found to be consistently rearranged in neoplasia-associated chromosome abnormalities in lipomas, myxoid liposarcomas, uterine leiomyomas, and pleomorphic adenomas of the salivary gland.

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In situ hybridization localizes the human putative oncogene GLI to chromosome subbands 12q13.3-14.1

Abstract

ASJC Scopus subject areas

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