In situ changes in purine nucleotide and n‐acetyl concentrations upon inducing global ischemia in cat brain

Peter C.M. van Zijl; Chrit T.W. Moonen

doi:10.1002/mrm.1910290315

In situ changes in purine nucleotide and n‐acetyl concentrations upon inducing global ischemia in cat brain

Peter C.M. van Zijl, Chrit T.W. Moonen

School of Medicine

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Spectral changes upon death (global ischemia) were recorded in situ in cat cerebral cortex. A rapid signal loss of 10 ± 4% in the N‐acetyl resonance was observed (five cases), after which it remained constant for 1 h. For the first time signal changes are reported for low‐field resonances, which are assigned to adenosine/inosine and hypoxanthine.

Original language	English (US)
Pages (from-to)	381-385
Number of pages	5
Journal	Magnetic resonance in medicine
Volume	29
Issue number	3
DOIs	https://doi.org/10.1002/mrm.1910290315
State	Published - Mar 1993

Keywords

N‐acetylaspartate
ischemia
magnetic resonance
purine nucleotide

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1002/mrm.1910290315

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title = "In situ changes in purine nucleotide and n‐acetyl concentrations upon inducing global ischemia in cat brain",

abstract = "Spectral changes upon death (global ischemia) were recorded in situ in cat cerebral cortex. A rapid signal loss of 10 ± 4% in the N‐acetyl resonance was observed (five cases), after which it remained constant for 1 h. For the first time signal changes are reported for low‐field resonances, which are assigned to adenosine/inosine and hypoxanthine.",

keywords = "N‐acetylaspartate, ischemia, magnetic resonance, purine nucleotide",

author = "{van Zijl}, {Peter C.M.} and Moonen, {Chrit T.W.}",

year = "1993",

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AB - Spectral changes upon death (global ischemia) were recorded in situ in cat cerebral cortex. A rapid signal loss of 10 ± 4% in the N‐acetyl resonance was observed (five cases), after which it remained constant for 1 h. For the first time signal changes are reported for low‐field resonances, which are assigned to adenosine/inosine and hypoxanthine.

KW - N‐acetylaspartate

KW - ischemia

KW - magnetic resonance

KW - purine nucleotide

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In situ changes in purine nucleotide and n‐acetyl concentrations upon inducing global ischemia in cat brain

Abstract

Keywords

ASJC Scopus subject areas

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