Impulsivity-related traits are associated with higher white blood cell counts

Angelina R. Sutin, Yuri Milaneschi, Alessandra Cannas, Luigi Ferrucci, Manuela Uda, David Schlessinger, Alan B. Zonderman, Antonio Terracciano

Research output: Contribution to journalArticle

Abstract

A chronically elevated white blood cell (WBC) count is a risk factor for morbidity and mortality. The present research tests whether facets of impulsivity - impulsiveness, excitement-seeking, self-discipline, and deliberation - are associated with chronically elevated WBC counts. Community-dwelling participants (N = 5,652) from Sardinia, Italy, completed a standard personality questionnaire and provided blood samples concurrently and again 3 years later. Higher scores on impulsivity, in particular impulsiveness and excitementseeking, were related to higher total WBC counts and higher lymphocyte counts at both time points. Impulsiveness was a predictor of chronic inflammation: for every standard deviation difference in this trait, there was an almost 25% higher risk of elevated WBC counts at both time points (OR = 1.23, 95% CI = 1.10-1.38). These associations were mediated, in part, by smoking and body mass index. The findings demonstrate that links between psychological processes and immunity are not limited to acute stressors; stable personality dispositions are associated with a chronic inflammatory state.

Original languageEnglish (US)
Pages (from-to)616-623
Number of pages8
JournalJournal of Behavioral Medicine
Volume35
Issue number6
DOIs
StatePublished - 2012
Externally publishedYes

Fingerprint

Impulsive Behavior
Leukocyte Count
Italy
Personality
Independent Living
Lymphocyte Count
Immunity
Body Mass Index
Smoking
Psychology
Inflammation
Morbidity
Mortality
Research

Keywords

  • Conscientiousness
  • Impulsivity
  • Inflammation
  • Neuroticism
  • Personality
  • White blood cells

ASJC Scopus subject areas

  • Psychology(all)
  • Psychiatry and Mental health

Cite this

Sutin, A. R., Milaneschi, Y., Cannas, A., Ferrucci, L., Uda, M., Schlessinger, D., ... Terracciano, A. (2012). Impulsivity-related traits are associated with higher white blood cell counts. Journal of Behavioral Medicine, 35(6), 616-623. https://doi.org/10.1007/s10865-011-9390-0

Impulsivity-related traits are associated with higher white blood cell counts. / Sutin, Angelina R.; Milaneschi, Yuri; Cannas, Alessandra; Ferrucci, Luigi; Uda, Manuela; Schlessinger, David; Zonderman, Alan B.; Terracciano, Antonio.

In: Journal of Behavioral Medicine, Vol. 35, No. 6, 2012, p. 616-623.

Research output: Contribution to journalArticle

Sutin, AR, Milaneschi, Y, Cannas, A, Ferrucci, L, Uda, M, Schlessinger, D, Zonderman, AB & Terracciano, A 2012, 'Impulsivity-related traits are associated with higher white blood cell counts', Journal of Behavioral Medicine, vol. 35, no. 6, pp. 616-623. https://doi.org/10.1007/s10865-011-9390-0
Sutin AR, Milaneschi Y, Cannas A, Ferrucci L, Uda M, Schlessinger D et al. Impulsivity-related traits are associated with higher white blood cell counts. Journal of Behavioral Medicine. 2012;35(6):616-623. https://doi.org/10.1007/s10865-011-9390-0
Sutin, Angelina R. ; Milaneschi, Yuri ; Cannas, Alessandra ; Ferrucci, Luigi ; Uda, Manuela ; Schlessinger, David ; Zonderman, Alan B. ; Terracciano, Antonio. / Impulsivity-related traits are associated with higher white blood cell counts. In: Journal of Behavioral Medicine. 2012 ; Vol. 35, No. 6. pp. 616-623.
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