Improving the tools of clinical pharmacology: Goals for 2017 and beyond

I. Zineh, D. Abernethy, C. E C A Hop, A. Bello, M. B. McClellan, G. W. Daniel, M. H. Romine

Research output: Contribution to journalArticle

Abstract

Current trends in pronounced late-stage attrition rates of promising drug candidates are a pressing concern for patients, providers, and other stakeholders across the health care system. Here, we describe six areas in which clinical pharmacology methods and frameworks can help ameliorate these trends in late-stage attrition and increase the efficiency of drug development and evaluation. These recommendations are based, in part, on previous stakeholder engagement and input, as well as a previously published white paper.

LanguageEnglish (US)
Pages22-24
Number of pages3
JournalClinical Pharmacology and Therapeutics
Volume101
Issue number1
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

Fingerprint

Drug Evaluation
Clinical Pharmacology
Delivery of Health Care
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Zineh, I., Abernethy, D., Hop, C. E. C. A., Bello, A., McClellan, M. B., Daniel, G. W., & Romine, M. H. (2017). Improving the tools of clinical pharmacology: Goals for 2017 and beyond. Clinical Pharmacology and Therapeutics, 101(1), 22-24. DOI: 10.1002/cpt.530

Improving the tools of clinical pharmacology : Goals for 2017 and beyond. / Zineh, I.; Abernethy, D.; Hop, C. E C A; Bello, A.; McClellan, M. B.; Daniel, G. W.; Romine, M. H.

In: Clinical Pharmacology and Therapeutics, Vol. 101, No. 1, 01.01.2017, p. 22-24.

Research output: Contribution to journalArticle

Zineh, I, Abernethy, D, Hop, CECA, Bello, A, McClellan, MB, Daniel, GW & Romine, MH 2017, 'Improving the tools of clinical pharmacology: Goals for 2017 and beyond' Clinical Pharmacology and Therapeutics, vol. 101, no. 1, pp. 22-24. DOI: 10.1002/cpt.530
Zineh I, Abernethy D, Hop CECA, Bello A, McClellan MB, Daniel GW et al. Improving the tools of clinical pharmacology: Goals for 2017 and beyond. Clinical Pharmacology and Therapeutics. 2017 Jan 1;101(1):22-24. Available from, DOI: 10.1002/cpt.530
Zineh, I. ; Abernethy, D. ; Hop, C. E C A ; Bello, A. ; McClellan, M. B. ; Daniel, G. W. ; Romine, M. H./ Improving the tools of clinical pharmacology : Goals for 2017 and beyond. In: Clinical Pharmacology and Therapeutics. 2017 ; Vol. 101, No. 1. pp. 22-24
@article{96033ea86b58406bb9f0f35ef0af9638,
title = "Improving the tools of clinical pharmacology: Goals for 2017 and beyond",
abstract = "Current trends in pronounced late-stage attrition rates of promising drug candidates are a pressing concern for patients, providers, and other stakeholders across the health care system. Here, we describe six areas in which clinical pharmacology methods and frameworks can help ameliorate these trends in late-stage attrition and increase the efficiency of drug development and evaluation. These recommendations are based, in part, on previous stakeholder engagement and input, as well as a previously published white paper.",
author = "I. Zineh and D. Abernethy and Hop, {C. E C A} and A. Bello and McClellan, {M. B.} and Daniel, {G. W.} and Romine, {M. H.}",
year = "2017",
month = "1",
day = "1",
doi = "10.1002/cpt.530",
language = "English (US)",
volume = "101",
pages = "22--24",
journal = "Clinical Pharmacology and Therapeutics",
issn = "0009-9236",
publisher = "Nature Publishing Group",
number = "1",

}

TY - JOUR

T1 - Improving the tools of clinical pharmacology

T2 - Clinical Pharmacology and Therapeutics

AU - Zineh,I.

AU - Abernethy,D.

AU - Hop,C. E C A

AU - Bello,A.

AU - McClellan,M. B.

AU - Daniel,G. W.

AU - Romine,M. H.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Current trends in pronounced late-stage attrition rates of promising drug candidates are a pressing concern for patients, providers, and other stakeholders across the health care system. Here, we describe six areas in which clinical pharmacology methods and frameworks can help ameliorate these trends in late-stage attrition and increase the efficiency of drug development and evaluation. These recommendations are based, in part, on previous stakeholder engagement and input, as well as a previously published white paper.

AB - Current trends in pronounced late-stage attrition rates of promising drug candidates are a pressing concern for patients, providers, and other stakeholders across the health care system. Here, we describe six areas in which clinical pharmacology methods and frameworks can help ameliorate these trends in late-stage attrition and increase the efficiency of drug development and evaluation. These recommendations are based, in part, on previous stakeholder engagement and input, as well as a previously published white paper.

UR - http://www.scopus.com/inward/record.url?scp=85006056656&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85006056656&partnerID=8YFLogxK

U2 - 10.1002/cpt.530

DO - 10.1002/cpt.530

M3 - Article

VL - 101

SP - 22

EP - 24

JO - Clinical Pharmacology and Therapeutics

JF - Clinical Pharmacology and Therapeutics

SN - 0009-9236

IS - 1

ER -