Improving dementia assessment by reducing sample heterogeneity

Research output: Contribution to journalArticle

Abstract

Outcome assessment for clinical dementia trials could be enhanced by using the Mini-mental State Examination (MMSE) and the Hopkins Verbal Learning Test (HVLT), in addition to imaging and genetic screening. The statistical power of trials could be increased if heterogeneity of the sample were reduced by the administration of a risk factor inventory which could be used for subject selection or selection of drug responders.

Original languageEnglish (US)
Pages (from-to)383-389
Number of pages7
JournalInternational psychogeriatrics
Volume19
Issue number3
DOIs
StatePublished - Jun 1 2007

Keywords

  • Clinical dementia trials
  • Hopkins Verbal Learning Test
  • Mini-mental State Examination
  • Outcome assessment

ASJC Scopus subject areas

  • Clinical Psychology
  • Gerontology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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