Improving dementia assessment by reducing sample heterogeneity

Research output: Contribution to journalArticle

Abstract

Outcome assessment for clinical dementia trials could be enhanced by using the Mini-mental State Examination (MMSE) and the Hopkins Verbal Learning Test (HVLT), in addition to imaging and genetic screening. The statistical power of trials could be increased if heterogeneity of the sample were reduced by the administration of a risk factor inventory which could be used for subject selection or selection of drug responders.

Original languageEnglish (US)
Pages (from-to)383-389
Number of pages7
JournalInternational Psychogeriatrics
Volume19
Issue number3
DOIs
StatePublished - Jun 2007

Fingerprint

Verbal Learning
Genetic Testing
Patient Selection
Dementia
Outcome Assessment (Health Care)
Clinical Trials
Equipment and Supplies
Pharmaceutical Preparations

Keywords

  • Clinical dementia trials
  • Hopkins Verbal Learning Test
  • Mini-mental State Examination
  • Outcome assessment

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Aging
  • Psychiatry and Mental health
  • Psychology(all)
  • Clinical Psychology

Cite this

Improving dementia assessment by reducing sample heterogeneity. / Folstein, Marshal F.

In: International Psychogeriatrics, Vol. 19, No. 3, 06.2007, p. 383-389.

Research output: Contribution to journalArticle

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