Improvement of sexual function in testosterone deficient men treated for 1 year with a permeation enhanced testosterone transdermal system

S. Arver; A. S. Dobs; A. W. Meikle; R. P. Allen; S. W. Sanders; N. A. Mazer

doi:10.1016/S0022-5347(01)66141-X

Improvement of sexual function in testosterone deficient men treated for 1 year with a permeation enhanced testosterone transdermal system

S. Arver, A. S. Dobs, A. W. Meikle, R. P. Allen, S. W. Sanders, N. A. Mazer

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: The effects of androgen replacement via a nonscrotal permeation enhanced testosterone transdermal system on the sexual function of men with hypogonadism were assessed. Materials and Methods: An open label, multicenter study of testosterone supplementation and withdrawal was conducted with sexual function assessed by the Watts and Davidson questionnaires and RigiScan* monitoring. Results: When comparing results obtained during use of the testosterone transdermal system (with normalized testosterone levels) and during the androgen withdrawal period, nocturnal erections occurred more frequently with longer duration and greater rigidity, and patient assessments of sexual desire and weekly number of erections were higher. Conclusions: Sexual function improved significantly in men with hypogonadism treated with the testosterone transdermal system.

Original language	English (US)
Pages (from-to)	1604-1608
Number of pages	5
Journal	Journal of Urology
Volume	155
Issue number	5
DOIs	https://doi.org/10.1016/S0022-5347(01)66141-X
State	Published - May 1996
Externally published	Yes

Keywords

impotence
penile erection
testosterone

ASJC Scopus subject areas

Urology

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title = "Improvement of sexual function in testosterone deficient men treated for 1 year with a permeation enhanced testosterone transdermal system",

abstract = "Purpose: The effects of androgen replacement via a nonscrotal permeation enhanced testosterone transdermal system on the sexual function of men with hypogonadism were assessed. Materials and Methods: An open label, multicenter study of testosterone supplementation and withdrawal was conducted with sexual function assessed by the Watts and Davidson questionnaires and RigiScan* monitoring. Results: When comparing results obtained during use of the testosterone transdermal system (with normalized testosterone levels) and during the androgen withdrawal period, nocturnal erections occurred more frequently with longer duration and greater rigidity, and patient assessments of sexual desire and weekly number of erections were higher. Conclusions: Sexual function improved significantly in men with hypogonadism treated with the testosterone transdermal system.",

keywords = "impotence, penile erection, testosterone",

author = "S. Arver and Dobs, {A. S.} and Meikle, {A. W.} and Allen, {R. P.} and Sanders, {S. W.} and Mazer, {N. A.}",

year = "1996",

month = may,

doi = "10.1016/S0022-5347(01)66141-X",

language = "English (US)",

volume = "155",

pages = "1604--1608",

journal = "Journal of Urology",

issn = "0022-5347",

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TY - JOUR

T1 - Improvement of sexual function in testosterone deficient men treated for 1 year with a permeation enhanced testosterone transdermal system

AU - Arver, S.

AU - Dobs, A. S.

AU - Meikle, A. W.

AU - Allen, R. P.

AU - Sanders, S. W.

AU - Mazer, N. A.

PY - 1996/5

Y1 - 1996/5

N2 - Purpose: The effects of androgen replacement via a nonscrotal permeation enhanced testosterone transdermal system on the sexual function of men with hypogonadism were assessed. Materials and Methods: An open label, multicenter study of testosterone supplementation and withdrawal was conducted with sexual function assessed by the Watts and Davidson questionnaires and RigiScan* monitoring. Results: When comparing results obtained during use of the testosterone transdermal system (with normalized testosterone levels) and during the androgen withdrawal period, nocturnal erections occurred more frequently with longer duration and greater rigidity, and patient assessments of sexual desire and weekly number of erections were higher. Conclusions: Sexual function improved significantly in men with hypogonadism treated with the testosterone transdermal system.

AB - Purpose: The effects of androgen replacement via a nonscrotal permeation enhanced testosterone transdermal system on the sexual function of men with hypogonadism were assessed. Materials and Methods: An open label, multicenter study of testosterone supplementation and withdrawal was conducted with sexual function assessed by the Watts and Davidson questionnaires and RigiScan* monitoring. Results: When comparing results obtained during use of the testosterone transdermal system (with normalized testosterone levels) and during the androgen withdrawal period, nocturnal erections occurred more frequently with longer duration and greater rigidity, and patient assessments of sexual desire and weekly number of erections were higher. Conclusions: Sexual function improved significantly in men with hypogonadism treated with the testosterone transdermal system.

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KW - penile erection

KW - testosterone

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Improvement of sexual function in testosterone deficient men treated for 1 year with a permeation enhanced testosterone transdermal system

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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