Improved noise propagation in statistical image reconstruction with resolution modeling

Arman Rahmim, Ju Chieh Cheng, Vesna Sossi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

23 Scopus citations

Abstract

Positron emission tomography (PET), like other imaging modalities, has resolution limitations. Two general/common approaches to improve reconstructed image resolution include: (i) the de-convolution scheme, and (ii) system matrix modeling (in statistical image reconstruction methods). An interesting observation about (ii) is that it is able to improve both resolution and noise characteristics of the reconstructed images (unlike (i) which offers a trade-off). In this work, we have used the unified noise model developed by Qi [5] to perform image covariance calculations without and with the inclusion of resolution modeling in the system matrix of the EM algorithm. We have in particular shown that, while system matrix modeling of finite resolution effects improves the image resolution by direct contribution to the reconstruction task, it is at the same time able to lower the reconstructed image noise due to a compression/widening effect in inter-voxel correlations. We have also experimentally verified this effect.

Original languageEnglish (US)
Title of host publication2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference
Pages2576-2578
Number of pages3
DOIs
StatePublished - Dec 1 2005
EventNuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico
Duration: Oct 23 2005Oct 29 2005

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume5
ISSN (Print)1095-7863

Other

OtherNuclear Science Symposium Conference Record, 2005 IEEE
Country/TerritoryPuerto Rico
Period10/23/0510/29/05

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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