Improved diagnostic yield of bronchoscopy in peripheral pulmonary lesions: Combination of radial probe endobronchial ultrasound and rapid on-site evaluation

Chia Hung Chen, Wen Chien Cheng, Biing Ru Wu, Chih Yu Chen, Wei Chun Chen, Te Chun Hsia, Wei Chih Liao, Chih Yen Tu, Chuen Ming Shih, Wu Huei Hsu, Ko Pen Wang

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Rapid on-site evaluation (ROSE) of cytologic specimens is a useful ancillary technique in needle aspiration procedures of pulmonary/mediastinal lesions, but few reports had been carried out to confirm the utility in the diagnosis of peripheral pulmonary lesions (PPLs) by radial probe endobronchial ultrasound (R-EBUS). Methods: To evaluate the impact of ROSE on the diagnostic yield of R-EBUS for PPLs, we retrospectively analyzed the diagnostic yields of transbronchial biopsy (TBB) or brushing using R-EBUS for patients with PPLs in a tertiary university hospital from December 2012 to December 2014. Results: A total of 815 patients with PPLs were included. A definite diagnosis was made by R-EBUS-guided TBB or brushing for 627 patients (76.9%). A total of 279 patients (34.2%) were examined by a ROSE technique. The combination of R-EBUS guided TBB or brushing with ROSE raised the diagnostic yield in the diagnosis of PPLs, especially difficult cases: right apical and left apical-posterior segment locations, small PPLs <3 cm without bronchus signs on computed tomography (CT) scan, PPLs with pleural effusions, and the position of probe is not within. Conclusions: ROSE can improve the PPLs diagnostic yield when using R-EBUS guided TBB or brushing.

Original languageEnglish (US)
Pages (from-to)S418-S425
JournalJournal of Thoracic Disease
Volume7
DOIs
StatePublished - Jan 1 2015

Keywords

  • Endobronchial ultrasound (EBUS)
  • Peripheral pulmonary lesion (PPL)
  • Rapid on-site evaluation (ROSE)

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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