Improved coronary artery definition with T2-weighted, free-breathing, three-dimensional coronary MRA

René M. Botnar, Matthias Stuber, Peter G. Danias, Kraig V. Kissinger, Warren J. Manning

Research output: Contribution to journalArticle

Abstract

Background - Three-dimensional (3D) navigator-gated and prospectively corrected free-breathing coronary magnetic resonance angiography (MRA) allows for submillimeter image resolution but suffers from poor contrast between coronary blood and myocardium. Data collected over >100 ms/heart beat are also susceptible to bulk cardiac and respiratory motion. To address these problems, we examined the effect of a T2 preparation prepulse (T2prep) for myocardial suppression and a shortened acquisition window on coronary definition. Methods and Results - Eight healthy adult subjects and 5 patients with confirmed coronary artery disease (CAD) underwent free-breathing 3D MRA with and without T2prep and with 120- and 60-ms data-acquisition windows. The T2prep resulted in a 123% (P

Original languageEnglish (US)
Pages (from-to)3139-3148
Number of pages10
JournalCirculation
Volume99
Issue number24
StatePublished - Jun 22 1999
Externally publishedYes

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Magnetic Resonance Angiography
Coronary Angiography
Coronary Vessels
Respiration
Coronary Artery Disease
Myocardium
Healthy Volunteers

Keywords

  • Angiography
  • Contrast media
  • Imaging
  • Vessels

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Botnar, R. M., Stuber, M., Danias, P. G., Kissinger, K. V., & Manning, W. J. (1999). Improved coronary artery definition with T2-weighted, free-breathing, three-dimensional coronary MRA. Circulation, 99(24), 3139-3148.

Improved coronary artery definition with T2-weighted, free-breathing, three-dimensional coronary MRA. / Botnar, René M.; Stuber, Matthias; Danias, Peter G.; Kissinger, Kraig V.; Manning, Warren J.

In: Circulation, Vol. 99, No. 24, 22.06.1999, p. 3139-3148.

Research output: Contribution to journalArticle

Botnar, RM, Stuber, M, Danias, PG, Kissinger, KV & Manning, WJ 1999, 'Improved coronary artery definition with T2-weighted, free-breathing, three-dimensional coronary MRA', Circulation, vol. 99, no. 24, pp. 3139-3148.
Botnar RM, Stuber M, Danias PG, Kissinger KV, Manning WJ. Improved coronary artery definition with T2-weighted, free-breathing, three-dimensional coronary MRA. Circulation. 1999 Jun 22;99(24):3139-3148.
Botnar, René M. ; Stuber, Matthias ; Danias, Peter G. ; Kissinger, Kraig V. ; Manning, Warren J. / Improved coronary artery definition with T2-weighted, free-breathing, three-dimensional coronary MRA. In: Circulation. 1999 ; Vol. 99, No. 24. pp. 3139-3148.
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