Importance of enhanced surveillance for prevention of pertussis in children

Angela Domínguez, Pere Godoy, Diana Toledo, Núria Soldevila, Manuel García-Cenoz, Gloria Farrús, Inma Crespo, Joan A. Caylà, Maria Rosa Sala, Neus Camps, Irene Barrabeig, Josep Alvarez

Research output: Contribution to journalArticle


Background: Bordetella pertussis infection causes considerable morbidity, even in countries with high vaccination coverage. Surveillance of pertussis is usually passive and based on mandatory reporting. We assessed the epidemiologic and clinical characteristics of pertussis cases detected by passive or enhanced surveillance. Methods: A prospective population-based study was carried out from January 2012 to December 2013 in Catalonia and Navarre, 2 Spanish regions with a total population of 8.2 million. For each confirmed case, variables of age, sex, clinical symptoms, laboratory results and vaccination status were investigated. Associations between the variables studied and the type of surveillance were assessed by odds ratio (OR) and its 95% confidence interval (CI). Logistic regression was used to estimate adjusted OR (aOR). Results: In children 1 year of age and suggests that providing clinics with free, fast laboratory diagnostic tests, together with enhanced surveillance of family contacts of any age is necessary to better determine existing cases. Enhanced surveillance may be helpful to better understand transmission patterns in the family and in the community.

Original languageEnglish (US)
Pages (from-to)729-733
Number of pages5
JournalPediatric Infectious Disease Journal
Issue number7
Publication statusPublished - Jul 4 2015
Externally publishedYes



  • case definition
  • enhanced surveillance
  • passive surveillance
  • pertussis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases
  • Microbiology (medical)

Cite this

Domínguez, A., Godoy, P., Toledo, D., Soldevila, N., García-Cenoz, M., Farrús, G., ... Alvarez, J. (2015). Importance of enhanced surveillance for prevention of pertussis in children. Pediatric Infectious Disease Journal, 34(7), 729-733.