Implications of the human immunodeficiency virus epidemic for control and eradication of measles

William J Moss, Felicity Cutts, Diane Griffin

Research output: Contribution to journalArticle

Abstract

Human immunodeficiency virus (HIV)-infected persons may be important, unrecognized transmitters of measles virus, thwarting eradication efforts. We reviewed the published English-language literature on measles and measles immunization in HIV-infected persons to investigate the clinical features of measles, the responses to measles immunization, and the safety of measles vaccine in HIV-infected persons and, conversely, the effect of measles and measles immunization on HIV infection. HIV-infected persons with measles are likely to have uncharacteristic clinical findings and severe illness, with high rates of pneumonitis and death. Primary and secondary failure of measles vaccine in HIV-infected children may permit transmission of measles virus in spite of high rates of immunization coverage. A factor that complicates measles-control efforts in areas of high prevalence of HIV is the potential for fatal infection with measles vaccine virus. Further research on the impact of the HIV epidemic on measles and measles immunization is necessary to guide strategies for the eradication of measles.

Original languageEnglish (US)
Pages (from-to)106-112
Number of pages7
JournalClinical Infectious Diseases
Volume29
Issue number1
StatePublished - 1999

Fingerprint

Measles
HIV
Immunization
Measles Vaccine
Measles virus
Virus Diseases
Pneumonia
Language
Safety

ASJC Scopus subject areas

  • Immunology

Cite this

Implications of the human immunodeficiency virus epidemic for control and eradication of measles. / Moss, William J; Cutts, Felicity; Griffin, Diane.

In: Clinical Infectious Diseases, Vol. 29, No. 1, 1999, p. 106-112.

Research output: Contribution to journalArticle

@article{8be012fa6d3a4606ae0d96aa4eefa2ca,
title = "Implications of the human immunodeficiency virus epidemic for control and eradication of measles",
abstract = "Human immunodeficiency virus (HIV)-infected persons may be important, unrecognized transmitters of measles virus, thwarting eradication efforts. We reviewed the published English-language literature on measles and measles immunization in HIV-infected persons to investigate the clinical features of measles, the responses to measles immunization, and the safety of measles vaccine in HIV-infected persons and, conversely, the effect of measles and measles immunization on HIV infection. HIV-infected persons with measles are likely to have uncharacteristic clinical findings and severe illness, with high rates of pneumonitis and death. Primary and secondary failure of measles vaccine in HIV-infected children may permit transmission of measles virus in spite of high rates of immunization coverage. A factor that complicates measles-control efforts in areas of high prevalence of HIV is the potential for fatal infection with measles vaccine virus. Further research on the impact of the HIV epidemic on measles and measles immunization is necessary to guide strategies for the eradication of measles.",
author = "Moss, {William J} and Felicity Cutts and Diane Griffin",
year = "1999",
language = "English (US)",
volume = "29",
pages = "106--112",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "1",

}

TY - JOUR

T1 - Implications of the human immunodeficiency virus epidemic for control and eradication of measles

AU - Moss, William J

AU - Cutts, Felicity

AU - Griffin, Diane

PY - 1999

Y1 - 1999

N2 - Human immunodeficiency virus (HIV)-infected persons may be important, unrecognized transmitters of measles virus, thwarting eradication efforts. We reviewed the published English-language literature on measles and measles immunization in HIV-infected persons to investigate the clinical features of measles, the responses to measles immunization, and the safety of measles vaccine in HIV-infected persons and, conversely, the effect of measles and measles immunization on HIV infection. HIV-infected persons with measles are likely to have uncharacteristic clinical findings and severe illness, with high rates of pneumonitis and death. Primary and secondary failure of measles vaccine in HIV-infected children may permit transmission of measles virus in spite of high rates of immunization coverage. A factor that complicates measles-control efforts in areas of high prevalence of HIV is the potential for fatal infection with measles vaccine virus. Further research on the impact of the HIV epidemic on measles and measles immunization is necessary to guide strategies for the eradication of measles.

AB - Human immunodeficiency virus (HIV)-infected persons may be important, unrecognized transmitters of measles virus, thwarting eradication efforts. We reviewed the published English-language literature on measles and measles immunization in HIV-infected persons to investigate the clinical features of measles, the responses to measles immunization, and the safety of measles vaccine in HIV-infected persons and, conversely, the effect of measles and measles immunization on HIV infection. HIV-infected persons with measles are likely to have uncharacteristic clinical findings and severe illness, with high rates of pneumonitis and death. Primary and secondary failure of measles vaccine in HIV-infected children may permit transmission of measles virus in spite of high rates of immunization coverage. A factor that complicates measles-control efforts in areas of high prevalence of HIV is the potential for fatal infection with measles vaccine virus. Further research on the impact of the HIV epidemic on measles and measles immunization is necessary to guide strategies for the eradication of measles.

UR - http://www.scopus.com/inward/record.url?scp=0032812676&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032812676&partnerID=8YFLogxK

M3 - Article

C2 - 10433572

AN - SCOPUS:0032812676

VL - 29

SP - 106

EP - 112

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

IS - 1

ER -