Implementing the 2017 McDonald criteria for the diagnosis of multiple sclerosis

Frauke Zipp, Jiwon Oh, Yara Dadalti Fragoso, Emmanuelle Waubant

Research output: Contribution to journalReview article

Abstract

The latest revision of the McDonald criteria for the diagnosis of multiple sclerosis (MS) was published online in 2017. New features of the criteria, which were designed to facilitate earlier diagnosis of MS, include the recognition of oligoclonal bands in the cerebrospinal fluid as a possible marker of dissemination of MS pathology in time, the introduction of symptomatic lesions as a parameter to demonstrate spatial or temporal pathology dissemination, and the use of cortical lesions to demonstrate dissemination in space. In this Viewpoint, a panel of world-renowned MS specialists share their personal experiences of the new criteria to date.

Original languageEnglish (US)
Pages (from-to)441-445
Number of pages5
JournalNature Reviews Neurology
Volume15
Issue number8
DOIs
StatePublished - Aug 1 2019
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience

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