Implementation of submandibular gland transfer: A multi-institutional study of feasibility and time to treatment

John Pang, Harry H. Ching, Ryan H. Sobel, Ryan K. Orosco, Joseph A. Califano, Robert C. Wang, Parag Sanghvi, Charles S. Coffey

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Submandibular gland transfer (SMGT) mitigates radiation-induced xerostomia but has yet to be widely adopted. We evaluate the feasibility of incorporating SMGT at multiple academic institutions and report the incidence of treatment delay. Methods: Forty-nine patients were identified who underwent SMGT. Time points pertaining to diagnosis and key treatment events including SMGT, surgery, chemotherapy, and radiation were extracted. Treatment delay was defined as either >60 days from diagnosis to definitive therapy or >6 weeks between surgery and adjuvant therapy. Results: Median time from diagnosis to primary treatment was 42 days (IQR, 32-54). Median time from surgery to adjuvant therapy was 33 days (IQR, 28-47). Delay in starting treatment was observed in 7/49 patients (14%). Six patients incurred a delay in postoperative radiation therapy (6/19; 32%). Conclusions: With appropriate care coordination, SMGT can be implemented into a clinical pathway with a goal of decreasing radiation-induced xerostomia without increasing treatment delays.

Original languageEnglish (US)
Pages (from-to)2182-2189
Number of pages8
JournalHead and Neck
Volume41
Issue number7
DOIs
StatePublished - Jul 2019

Keywords

  • head and neck cancer
  • radiation
  • salivary gland
  • submandibular gland transfer
  • xerostomia

ASJC Scopus subject areas

  • Otorhinolaryngology

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