Abstract
Objective:To implement feeding guidelines to reduce advancement time and the incidence of parenteral nutrition-associated liver disease (PNALD) among intestinal surgical infants requiring parenteral nutrition (PN).Study Design:Feeding guidelines with higher initial enteral nutrition (EN) volume and specific advancement criteria were implemented for surgical infants aged <6 months. Preimplementation and postimplementation outcomes were compared.Results:There were 57 preimplementation and 33 postimplementation infants. The initial EN volume improved from 10 to 20 ml kg -1 day -1 (P<0.001). Time to reach 50% of goal calories from EN decreased by a median of 6 days (P=0.012) without a change in necrotizing enterocolitis incidence after resuming feeding. PNALD incidence decreased from 70% to 48% (P=0.046), and median peak direct bilirubin (DB) decreased from 5.6 to 2.3 mg dl -1 (P=0.011).Conclusion:Feeding guideline implementation with higher initial feeding volume was well tolerated and resulted in faster achievement of 50% goal EN calories. PNALD incidence and peak DB were reduced.
Original language | English (US) |
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Pages (from-to) | 941-948 |
Number of pages | 8 |
Journal | Journal of Perinatology |
Volume | 35 |
Issue number | 11 |
DOIs | |
State | Published - Nov 1 2015 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Obstetrics and Gynecology