ImplementaciÓn de un sistema de telediagnÓstico de tuberculosis y determinaciÓn de multidrogorresistencia basada en el mÉtodo mods en Trujillo, PerÚ

Translated title of the contribution: Implementation of a telediagnostic system for tuberculosis and determination of multi-drug resistance based in the mods method in Trujillo, Peru

Luis Rodríguez, Alicia Alva, Jorge Coronel, Luz Caviedes, Alberto Mendoza-Ticona, Robert Gilman, Patricia Sheen, Mirko Zimic

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives. To implement a system for remote diagnosis of tuberculosis and multidrug resistance (MDR) using the Microscopic-Observation Drug Susceptibility Assay (MODS) method in the Mycobacteria Laboratory, Trujillo Center of Excellence in Tuberculosis (CENEX-Trujillo). The system included a variant of an algorithm for recognition of Mycobacterium tuberculosis recently reported from digital images of MODS cultures of sputum samples. Materials and methods. The recognition algorithm was optimized using a retraining statistical model based on digital images of MODS cultures from CENEX-Trujillo. Images of 50 positive MODS cultures of patients with suspected multidrug-resistant tuberculosis were obtained between January and October 2012 in the CENEX-Trujillo. Results. The sensitivity and specificity to recognize strings of tuberculosis were 92.04% and 94.93% respectively using objects. The sensitivity and specificity to determine a positive tuberculosis field were 95.4% and 98.07% respectively using pictures. Conclusions. The results demonstrated the feasibility of the implementation of telediagnostics in remote locations, which may contribute to the early detection of multidrug-resistant tuberculosis by MODS method.

Translated title of the contributionImplementation of a telediagnostic system for tuberculosis and determination of multi-drug resistance based in the mods method in Trujillo, Peru
Original languageSpanish
Pages (from-to)445-453
Number of pages9
JournalRevista Peruana de Medicina Experimental y Salud Publica
Volume31
Issue number3
StatePublished - Jan 1 2014
Externally publishedYes

Keywords

  • Multidrug-resistant
  • Multiple organ failure
  • Mycobacterium tuberculosis
  • Tuberculosis

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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