Implantable neurotechnologies: electrical stimulation and applications

Sudip Nag, Nitish V. Thakor

Research output: Contribution to journalReview article

Abstract

Neural stimulation using injected electrical charge is widely used both in functional therapies and as an experimental tool for neuroscience applications. Electrical pulses can induce excitation of targeted neural pathways that aid in the treatment of neural disorders or dysfunction of the central and peripheral nervous system. In this review, we summarize the recent trends in the field of electrical stimulation for therapeutic interventions of nervous system disorders, such as for the restoration of brain, eye, ear, spinal cord, nerve and muscle function. Neural prosthetic applications are discussed, and functional electrical stimulation parameters for treating such disorders are reviewed. Important considerations for implantable packaging and enhancing device reliability are also discussed. Neural stimulators are expected to play a profound role in implantable neural devices that treat disorders and help restore functions in injured or disabled nervous system.

Original languageEnglish (US)
Pages (from-to)63-76
Number of pages14
JournalMedical and Biological Engineering and Computing
Volume54
Issue number1
DOIs
StatePublished - Jan 1 2016

Keywords

  • Biphasic constant current
  • Charge injection
  • Charge-balanced stimulator
  • Energy efficiency
  • Functional electrical stimulation
  • Neural prostheses
  • Voltage compliance

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computer Science Applications

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