TY - JOUR
T1 - Impairment of work productivity in panic disorder patients
AU - Park, Yu Lee
AU - Kim, Won
AU - Chae, Jeong Ho
AU - Oh, Kang Seo
AU - Frick, Kevin D.
AU - Woo, Jong Min
N1 - Funding Information:
This work was supported by Grant from Inje University, 2008 and by GSK Korea. The choice of medication was not influenced by the sponsor organization′s interest, and the funding resources had no impact on data analysis, interpretation, and the report of the result as well as the study design.
PY - 2014/3/20
Y1 - 2014/3/20
N2 - Background Panic disorder (PD) has a critical impact on productivity at the workplace. This study aimed to identify the lost productivity time (LPT) for patients with PD. It also assessed change in LPT for patients with PD after 12 weeks of treatment with Selective Serotonin Reuptake Inhibitors (SSRIs), compared with healthy controls. Methods Working patients diagnosed with PD without other major medical or psychiatric illness were enrolled at outpatient psychiatric clinics (N=108). Age and sex-matched healthy controls were recruited through advertisement (N=108). Health and productivity, PD symptoms, and depressive symptoms were assessed using the Korean version of the World Health Organization's Health and Work Performance Questionnaire (HPQ), the Panic Disorder Severity Scale (PDSS), and the Hamilton Rating Scales for Depression (HAM-D), respectively at baseline, week 4, and week 12. Results At baseline, the PD group showed significantly higher LPT compared to the control group (103.02 vs. 47.28 h in the past 4 weeks). After 12 weeks of treatment, the PD group displayed significant clinical improvement as well as improved productivity with a marked reduction in LPT. Among the patients who completed the treatment, LPT due to PD was reduced from 104.38 to 55.15 h in the past 4 weeks. Limitations There may be selection bias due to case-control study design. Conclusions These data suggest that, after the treatment, there was significant improvement in clinical symptoms, and that productivity loss due to PD was almost entirely recovered to the level of healthy controls after 12 weeks of psychiatric outpatient treatment.
AB - Background Panic disorder (PD) has a critical impact on productivity at the workplace. This study aimed to identify the lost productivity time (LPT) for patients with PD. It also assessed change in LPT for patients with PD after 12 weeks of treatment with Selective Serotonin Reuptake Inhibitors (SSRIs), compared with healthy controls. Methods Working patients diagnosed with PD without other major medical or psychiatric illness were enrolled at outpatient psychiatric clinics (N=108). Age and sex-matched healthy controls were recruited through advertisement (N=108). Health and productivity, PD symptoms, and depressive symptoms were assessed using the Korean version of the World Health Organization's Health and Work Performance Questionnaire (HPQ), the Panic Disorder Severity Scale (PDSS), and the Hamilton Rating Scales for Depression (HAM-D), respectively at baseline, week 4, and week 12. Results At baseline, the PD group showed significantly higher LPT compared to the control group (103.02 vs. 47.28 h in the past 4 weeks). After 12 weeks of treatment, the PD group displayed significant clinical improvement as well as improved productivity with a marked reduction in LPT. Among the patients who completed the treatment, LPT due to PD was reduced from 104.38 to 55.15 h in the past 4 weeks. Limitations There may be selection bias due to case-control study design. Conclusions These data suggest that, after the treatment, there was significant improvement in clinical symptoms, and that productivity loss due to PD was almost entirely recovered to the level of healthy controls after 12 weeks of psychiatric outpatient treatment.
KW - Lost productivity time
KW - Panic disorder
KW - Productivity
KW - SSRIs
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U2 - 10.1016/j.jad.2013.12.021
DO - 10.1016/j.jad.2013.12.021
M3 - Article
C2 - 24581829
AN - SCOPUS:84893307465
SN - 0165-0327
VL - 157
SP - 60
EP - 65
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
ER -