Impact upon clinical outcomes of translation of PNA FISH-generated laboratory data from the clinical microbiology bench to bedside in real time

Tam Ly, Jyoti Gulia, Vasilios Pyrgos, Masashi Waga, Shmuel Shoham

Research output: Contribution to journalArticlepeer-review

Abstract

Fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) differentiates Staphylococcus aureus from other Gram-positive-cocci in clusters (GPCC). 101/202 patients with GPCC+ blood cultures were randomly assigned to clinician-notification of PNA FISH results. Notification was associated with reduced mortality (8% vs. 17%, p = 0.05), further antibiotic use (median -2.5 days, p = 0.01), and trended toward reduced hospital stay and charges.

Original languageEnglish (US)
Pages (from-to)637-640
Number of pages4
JournalTherapeutics and Clinical Risk Management
Volume4
Issue number3
StatePublished - Jul 29 2008
Externally publishedYes

ASJC Scopus subject areas

  • Safety Research
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)
  • Chemical Health and Safety

Fingerprint

Dive into the research topics of 'Impact upon clinical outcomes of translation of PNA FISH-generated laboratory data from the clinical microbiology bench to bedside in real time'. Together they form a unique fingerprint.

Cite this