TY - JOUR
T1 - Impact of the rotavirus vaccine in Valladolid, Spain
T2 - An interrupted time series analysis
AU - Pérez-Rubio, Alberto
AU - Luquero, Francisco Javier
AU - Bachiller Luque, Maria Rosario
AU - De La Torre Pardo, Paz
AU - Eiros Bouza, José María
PY - 2016
Y1 - 2016
N2 - Rotavirus vaccines (RV) have decreased the infant morbidity and mortality in countries that included RV in their national schedule. Rotavirus vaccination is recommended by the Spanish Society of Pediatrics; however, Spain, as most countries in Europe, has authorized commercialization but not included RV in its national vaccination program. We assessed the impact of RV on the rotavirus hospitalization rate through an interrupted time series analysis. There was a 46.8% (95% CI: 29.3-60.2) decrease on the rotavirus hospitalizations rate in the study region after RV commercialization in 2006. Currently there is limited evidence about the impact of RV in Europe, especially among countries not offering systematic vaccination in their national schedule. Documentation of RV coverage, effectiveness and impact is urgently needed in these countries.
AB - Rotavirus vaccines (RV) have decreased the infant morbidity and mortality in countries that included RV in their national schedule. Rotavirus vaccination is recommended by the Spanish Society of Pediatrics; however, Spain, as most countries in Europe, has authorized commercialization but not included RV in its national vaccination program. We assessed the impact of RV on the rotavirus hospitalization rate through an interrupted time series analysis. There was a 46.8% (95% CI: 29.3-60.2) decrease on the rotavirus hospitalizations rate in the study region after RV commercialization in 2006. Currently there is limited evidence about the impact of RV in Europe, especially among countries not offering systematic vaccination in their national schedule. Documentation of RV coverage, effectiveness and impact is urgently needed in these countries.
KW - Hospitalization
KW - Impact
KW - Rotavirus
KW - Time series analysis
UR - http://www.scopus.com/inward/record.url?scp=84964632491&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84964632491&partnerID=8YFLogxK
U2 - 10.1016/j.trivac.2016.04.005
DO - 10.1016/j.trivac.2016.04.005
M3 - Article
AN - SCOPUS:84964632491
SN - 1879-4378
VL - 5
SP - 84
EP - 87
JO - Trials in Vaccinology
JF - Trials in Vaccinology
ER -