Objective: To assess the impact of supplementing newborn infants with vitamin A on mortality at age 6 months. Design: Community based, randomised, double blind, placebo controlled trial. Setting: Two rural districts of Tamil Nadu, southern India. Participants: 11 619 newborn infants allocated 24 000 IU oral vitamin A or placebo on days 1 and 2 after delivery. Main outcome measure: Primary outcome measure was mortality at age 6 months. Results: Infants in the vitamin A group had a 22% reduction in total mortality (95% confidence interval 4% to 37%) compared with those in the placebo group. Vitamin A had an impact on mortality between two weeks and three months after treatment, with no additional impact after three months. Conclusion: Supplementing newborn infants with vitamin A can significantly reduce early infant mortality.
|Original language||English (US)|
|Number of pages||4|
|Journal||British medical journal|
|State||Published - Aug 2 2003|
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