Impact of self-reported guideline compliance: Bloodstream infection prevention in a national collaborative

Yea Jen Hsu, Kristina Weeks, Ting Yang, Melinda D. Sawyer, Jill A. Marsteller

Research output: Contribution to journalArticle


Background We sought to examine self-reported compliance with 5 evidence-based central line-associated bloodstream infection (CLABSI) prevention practices and link compliance to CLABSI rates in a national patient safety collaborative. Methods We analyzed data from a national CLABSI prevention program. Adult ICUs participating in the program submitted their CLABSI rates and a Team Checkup Tool (TCT) on a monthly basis. The TCT responses provided self-reported perceptions about how reliably the unit team performed the evidence-based practices in the previous month. Monthly data were aggregated into quarters for the analysis. We analyzed a total of 2775 ICU quarters during the program. Results Chlorhexidine skin preparation and hand hygiene had the highest adherence. Avoidance of the femoral site and removal of unnecessary lines had the lowest compliance. Regression results showed that consistent performance of all practices was significantly associated with lower CLABSI rates. In terms of each practice's independent effect, femoral site avoidance for line placement and removal of unnecessary lines were independently associated with lower CLABSI rates after controlling for other factors. Conclusion Our findings suggest that uptake of the 2 low-compliance practices, avoidance of the femoral site and removal of unnecessary lines, is important for reducing CLABSI rates in conjunction with other practices.

Original languageEnglish (US)
Pages (from-to)S191-S196
JournalAmerican Journal of Infection Control
Issue number10
StatePublished - Oct 1 2014


  • Central line-associated bloodstream infections
  • Guidelines
  • Hospital-acquired infection
  • Intensive care unit

ASJC Scopus subject areas

  • Epidemiology
  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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