Impact of scar, viable myocardium, and epicardial fat on substrate identification of ventricular tachycardia in a case with nonischemic cardiomyopathy

Takeshi Sasaki, James Mudd, Charles Jr Steenbergen, Menekhem M. Zviman, Christopher Miller, Saman Nazarian

Research output: Contribution to journalArticle

Abstract

A 56-year-old man with nonischemic cardiomyopathy underwent orthotopic cardiac transplantation after endocardial and epicardial radiofrequency catheter ablation for pleomorphic ventricular tachycardia. The myocardial substrate and epicardial fat were comprehensively analyzed with three-dimensional electroanatomic maps, late gadolinium enhanced ex-vivo cardiac magnetic resonance, and histological examination. The association of scar, viable myocardium, and epicardial fat with endocardial and epicardial electrogram voltage and duration was quantitatively defined. This case provides a unique opportunity to explore the reliability of electrical surrogates of scar in nonischemic cardiomyopathy. (PACE 2012;35:e345-e348)

Original languageEnglish (US)
JournalPACE - Pacing and Clinical Electrophysiology
Volume35
Issue number12
DOIs
StatePublished - Dec 2012

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Ventricular Tachycardia
Cardiomyopathies
Cicatrix
Myocardium
Fats
Catheter Ablation
Gadolinium
Heart Transplantation
Magnetic Resonance Spectroscopy

Keywords

  • magnetic resonance imaging
  • nonishcemic cardiomyopathy
  • ventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Impact of scar, viable myocardium, and epicardial fat on substrate identification of ventricular tachycardia in a case with nonischemic cardiomyopathy. / Sasaki, Takeshi; Mudd, James; Steenbergen, Charles Jr; Zviman, Menekhem M.; Miller, Christopher; Nazarian, Saman.

In: PACE - Pacing and Clinical Electrophysiology, Vol. 35, No. 12, 12.2012.

Research output: Contribution to journalArticle

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